{"id":"W1970256894","doi":"10.1002/1098-1136(200009)31:3<241::aid-glia50>3.0.co;2-9","title":"Thioredoxin reductase and glutathione synthesis is upregulated byt-butylhydroquinone in cortical astrocytes but not in cortical neurons","year":2000,"lang":"en","type":"article","venue":"Glia","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cameco (Canada); University of Saskatchewan","funders":"","keywords":"Thioredoxin reductase; Glutathione reductase; Thioredoxin; Glutathione; Biology; Antioxidant; Biochemistry; Reductase; Glutaredoxin; Cell biology; Enzyme; Glutathione peroxidase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002372771,0.0002452703,0.0003223271,0.00008528467,0.00006428715,0.00002431151,0.0002142676,0.0003427948,0.0002591279],"category_scores_gemma":[0.0003643416,0.0002470035,0.00006196173,0.0001687054,0.0003728915,0.00000668859,0.0001308034,0.0003372474,0.00004581111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002956087,"about_ca_system_score_gemma":0.00006273256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008485945,"about_ca_topic_score_gemma":0.0000686037,"domain_scores_codex":[0.9980009,0.0002712797,0.0004347132,0.000652383,0.0001323504,0.0005083418],"domain_scores_gemma":[0.9992288,0.0001214618,0.00004626749,0.0004277374,0.00002874729,0.0001469902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007658639,0.0002006805,0.008335191,0.000009414896,0.00002815596,0.0001076746,0.00008430577,0.00003223918,0.9869271,0.00004309971,0.0004036407,0.003062652],"study_design_scores_gemma":[0.001337426,0.0004296895,0.1540473,0.00004066114,0.00003584753,0.0002541979,0.00007865306,0.00137458,0.8404313,0.00008327817,0.001469668,0.0004174656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982858,0.0003788886,0.00001748733,0.0005070278,0.00009695708,0.0001887022,0.00005936277,0.00002246104,0.0004433081],"genre_scores_gemma":[0.9979722,0.000261978,0.0007621279,0.0005273769,0.00009688032,0.00003926492,0.00005066082,0.00002646154,0.0002630816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1464958,"threshold_uncertainty_score":0.9999982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009826401938552156,"score_gpt":0.2406995555510531,"score_spread":0.2308731536125009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}