{"id":"W1970298367","doi":"10.1158/1535-7163.pms-ia7","title":"Abstract IA7: Chromosome instability and synthetic lethality in yeast and cancer","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Synthetic lethality; Biology; Cohesin; Gene; Mutant; Genetics; DNA replication; DNA repair; Mutation; Molecular biology; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001372064,0.0005609067,0.0003050114,0.0006316731,0.0003403607,0.0004982748,0.0004074191,0.0004484578,0.004241941],"category_scores_gemma":[0.000137833,0.0001228369,0.0002924892,0.000420866,0.0002395155,0.0001175649,0.0006234394,0.0005746419,0.001834843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005899082,"about_ca_system_score_gemma":0.0003054602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00152762,"about_ca_topic_score_gemma":0.001058993,"domain_scores_codex":[0.9998825,0.0000193496,0.00001054583,0.00001953425,0.00004491719,0.0000232487],"domain_scores_gemma":[0.9998688,0.00001556562,0.00003474652,0.00001403439,0.00002358658,0.00004317307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006024288,0.0001024963,0.003252753,0.0002675919,0.00007264208,0.001613174,0.00003713649,0.000957549,0.9649025,0.003729859,0.004662993,0.01979889],"study_design_scores_gemma":[0.0001349649,0.0008442118,0.04408213,0.0001213217,0.0001724765,0.009802166,0.0002306754,0.01013164,0.8226438,0.003514397,0.1082622,0.00006007688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9094118,0.02639571,0.01590516,0.001793311,0.0005921578,0.0001088273,0.007555579,0.002309962,0.03592747],"genre_scores_gemma":[0.9820454,0.002907371,0.001850774,0.0002438311,0.00003174369,0.00004354359,0.004195645,0.0000973604,0.008584449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004241941,"threshold_uncertainty_score":0.01419073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02327029834187335,"score_gpt":0.3006767746937523,"score_spread":0.2774064763518789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}