{"id":"W1970310716","doi":"10.1016/j.neurobiolaging.2012.08.003","title":"Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β","year":2012,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Henry Smith Charity; Alzheimer Society","keywords":"Leptin; Hippocampal formation; Long-term potentiation; Leptin receptor; Endocrinology; Chemistry; Internal medicine; Neuroscience; Cell biology; Biology; Receptor; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003228822,0.0007449517,0.0009139921,0.0006535262,0.0004311557,0.0006197625,0.0006918625,0.0008745355,0.002216644],"category_scores_gemma":[0.000509946,0.0004249733,0.000532679,0.0003743501,0.001054998,0.0009035781,0.0004726086,0.001960286,0.0004892003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004955775,"about_ca_system_score_gemma":0.0009849942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002022202,"about_ca_topic_score_gemma":0.003767563,"domain_scores_codex":[0.9997051,0.00003703988,0.00004963428,0.00004663167,0.000039509,0.0001220799],"domain_scores_gemma":[0.9995389,0.00004195306,0.0001168516,0.00006766966,0.00005303146,0.0001816304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01380583,0.0007238559,0.0005689402,0.0002509275,0.0001303616,0.0005507384,0.0001190837,0.0002038677,0.9741732,0.0005236911,0.000386738,0.008562632],"study_design_scores_gemma":[0.001073582,0.004803572,0.007869527,0.00006627033,0.0001962941,0.0007599224,0.0005791336,0.0008749319,0.9798737,0.0007535698,0.003104947,0.00004462276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943274,0.002579354,0.001132099,0.0004158535,0.0001837086,0.00003857115,0.0003201577,0.0001348581,0.0008680421],"genre_scores_gemma":[0.9908248,0.002820322,0.001447208,0.000163139,0.00005027498,0.00008434994,0.0003633295,0.00004786428,0.004198689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002216644,"threshold_uncertainty_score":0.007415414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02607755621648548,"score_gpt":0.2641996652795741,"score_spread":0.2381221090630886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}