{"id":"W1970364105","doi":"10.1016/j.transproceed.2008.01.054","title":"“Indirect” Acute Islet Allograft Destruction in Nonobese Diabetic Mice Is Independent of Donor Major Histocompatibility Complex and Requires Host B Lymphocytes","year":2008,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"U.S. Public Health Service","keywords":"NOD mice; Nod; Immunology; Major histocompatibility complex; Islet; Insulitis; Biology; Autoimmunity; Transplantation; Immune system; Medicine; Diabetes mellitus; Endocrinology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008933044,0.001342897,0.0004961251,0.0008500302,0.0003252938,0.0009076102,0.0004877158,0.0007382734,0.003443773],"category_scores_gemma":[0.0003823158,0.0003814419,0.0006036924,0.0003401087,0.0008421988,0.0007697773,0.0006142969,0.002238827,0.0007682809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002123032,"about_ca_system_score_gemma":0.000247334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001371241,"about_ca_topic_score_gemma":0.0002761792,"domain_scores_codex":[0.9992686,0.0001378367,0.00008078951,0.000142152,0.0001808674,0.0001898493],"domain_scores_gemma":[0.9989212,0.0001463293,0.0003409496,0.000239705,0.00004654393,0.0003053088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002167134,0.0003071362,0.001617409,0.0001587782,0.00002958909,0.0004840558,0.00005101446,0.00007904373,0.9899417,0.0007795382,0.0001218371,0.004262797],"study_design_scores_gemma":[0.0002808792,0.001960281,0.01902158,0.00003975547,0.0001077229,0.003206873,0.0001317571,0.0007700234,0.9719748,0.0005390934,0.001951889,0.00001538544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910132,0.001272313,0.003065501,0.0001359506,0.00009294173,0.00003645253,0.0001988438,0.000202357,0.003982321],"genre_scores_gemma":[0.9931579,0.0007675425,0.002100475,0.000161836,0.00009480683,0.00006417361,0.0003529697,0.00006637995,0.003233819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003443773,"threshold_uncertainty_score":0.01152056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02305242750407673,"score_gpt":0.2551696682559667,"score_spread":0.2321172407518899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}