{"id":"W1970426618","doi":"10.1111/j.1365-2567.2004.01884.x","title":"The mechanism for activation of the neutrophil NADPH‐oxidase by the peptides formyl‐Met‐Leu‐Phe and Trp‐Lys‐Tyr‐Met‐Val‐Met differs from that for interleukin‐8","year":2004,"lang":"en","type":"article","venue":"Immunology","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Svenska Läkaresällskapet; Royal Society","keywords":"Chemotaxis; NADPH oxidase; N-Formylmethionine leucyl-phenylalanine; Pertussis toxin; Formyl peptide receptor; Cell biology; Biology; Superoxide; Receptor; Agonist; Signal transduction; Biochemistry; G protein; Reactive oxygen species; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186334,0.0002115835,0.0002109583,0.00002393738,0.0004060536,0.00004201553,0.0004931871,0.0002192898,0.000003212943],"category_scores_gemma":[0.0001926074,0.0001122476,0.0002080443,0.00005964855,0.0003208733,0.00001170503,0.0001945798,0.0001358111,6.657501e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002995524,"about_ca_system_score_gemma":0.00005788301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002400701,"about_ca_topic_score_gemma":0.0001178922,"domain_scores_codex":[0.9989542,0.00007881331,0.0002480684,0.0003191852,0.00008404906,0.0003156826],"domain_scores_gemma":[0.9989473,0.000157059,0.0002301054,0.0005380835,0.0001018173,0.00002569342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004485423,0.0000518677,0.00007167596,0.000009928604,0.0002465184,1.295592e-7,0.0001761092,0.000004468106,0.9727741,0.005714179,0.0002690784,0.02023334],"study_design_scores_gemma":[0.002020695,0.001299988,0.0008259959,0.00002820627,0.00005713102,0.000007729909,0.0008822994,0.00001693044,0.9627807,0.01960018,0.01232511,0.0001550454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887785,0.001808788,0.006338286,0.001623613,0.0003244276,0.000894503,0.000184997,0.0000107211,0.00003619577],"genre_scores_gemma":[0.9975789,0.0005034407,0.0005664675,0.0005451647,0.0001300898,0.0003361884,0.0000965312,0.000032156,0.0002110329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02007829,"threshold_uncertainty_score":0.4577323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009067867213166865,"score_gpt":0.2213656878409651,"score_spread":0.2122978206277983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}