{"id":"W1970428129","doi":"10.4161/auto.7.1.13840","title":"Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase","year":2010,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; McGill University; University of Toronto; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Biotechnology and Biological Sciences Research Council; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Endoplasmic reticulum; Biology; Autophagosome; Golgi apparatus; ATG16L1; GTPase; ATG8; Cytoplasm; Phagosome; BAG3; Small GTPase; Biochemistry; Signal transduction; Intracellular; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017672,0.0002860943,0.0003045265,0.0002880748,0.0003300712,0.0003710975,0.0001382522,0.0003284349,0.0006448802],"category_scores_gemma":[0.0001636707,0.0001623328,0.000304359,0.0001913797,0.0003135304,0.0004325651,0.0003081103,0.0003938375,0.0004588267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004911485,"about_ca_system_score_gemma":0.0002537167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002525826,"about_ca_topic_score_gemma":0.0004327591,"domain_scores_codex":[0.9998425,0.00002550236,0.00001084166,0.00003532978,0.00004691649,0.0000388248],"domain_scores_gemma":[0.9998918,0.00002040159,0.00003838461,0.00001672948,0.00001630246,0.00001644428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001376806,0.00002073842,0.000710161,0.00007610306,0.000007113227,0.0002392588,0.00002048413,0.00005248034,0.9951018,0.0004984955,0.0001209864,0.003014673],"study_design_scores_gemma":[0.000007752466,0.00007898078,0.01069933,0.000008374112,0.00001120711,0.001125764,0.00003145989,0.0006361066,0.9835133,0.0002462764,0.00363595,0.000005468854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865437,0.003946893,0.005226834,0.0001981844,0.00002244769,0.00001720425,0.00025685,0.0001424579,0.003645465],"genre_scores_gemma":[0.9950059,0.001316279,0.001930081,0.00004381912,0.000007477018,0.00001293719,0.0003540093,0.00001638746,0.001313046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006448802,"threshold_uncertainty_score":0.003563523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005682605973062273,"score_gpt":0.2448687894451079,"score_spread":0.2391861834720456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}