{"id":"W1970428129","doi":"10.4161/auto.7.1.13840","title":"Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase","year":2010,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; McGill University; University of Toronto; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Biotechnology and Biological Sciences Research Council; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Endoplasmic reticulum; Biology; Autophagosome; Golgi apparatus; ATG16L1; GTPase; ATG8; Cytoplasm; Phagosome; BAG3; Small GTPase; Biochemistry; Signal transduction; Intracellular; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002769059,0.0003383336,0.0005746037,0.0001116995,0.0002427785,0.00002969385,0.0002972618,0.0002711178,0.001048676],"category_scores_gemma":[0.0002538225,0.0002356928,0.0002629047,0.0002698837,0.0006865493,0.0001356844,0.0002350633,0.0004137816,0.00005275415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004207613,"about_ca_system_score_gemma":0.0002238415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006437568,"about_ca_topic_score_gemma":0.00004033934,"domain_scores_codex":[0.9979459,0.0001129894,0.0005328264,0.0004908894,0.0004383264,0.0004790638],"domain_scores_gemma":[0.9981385,0.0001689955,0.0002928642,0.001012196,0.0001057188,0.0002817548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005853539,0.0002806473,0.007470187,0.0001036212,0.0001741745,0.0001459683,0.0004987194,7.278846e-7,0.9823419,0.005924203,0.001044941,0.00142959],"study_design_scores_gemma":[0.004336655,0.0002666451,0.3011058,0.0000566453,0.0002425041,0.0003526559,0.000037777,0.0001409201,0.6829055,0.00119119,0.009119107,0.0002446262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936973,0.0005417212,0.00001110484,0.0006364365,0.001709073,0.0006230728,0.00005710605,0.000130371,0.002593779],"genre_scores_gemma":[0.9961315,0.0001545957,0.0002942579,0.0008512272,0.0004346837,0.00002818424,0.00002953284,0.00005347274,0.002022567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2994364,"threshold_uncertainty_score":0.9998645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005682605973062273,"score_gpt":0.2448687894451079,"score_spread":0.2391861834720456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}