{"id":"W1970444794","doi":"10.1042/bst0311390","title":"Toxicity of glyoxals – role of oxidative stress, metabolic detoxification and thiamine deficiency","year":2003,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; University of Toronto","funders":"","keywords":"Thiamine; Glutathione; Chemistry; Glyoxal; Oxidative stress; Biochemistry; Transketolase; Cytotoxicity; Methylglyoxal; Glycation; Hepatocyte; Antioxidant; Metabolism; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002033256,0.0004419108,0.0002907951,0.0002098623,0.0001358976,0.000344433,0.0001948956,0.0004150512,0.0006752126],"category_scores_gemma":[0.0001469257,0.0001199153,0.0002699762,0.0001478399,0.0003851409,0.0004266996,0.0002940645,0.0003007574,0.0001083529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002628696,"about_ca_system_score_gemma":0.0001454823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004724069,"about_ca_topic_score_gemma":0.0004839003,"domain_scores_codex":[0.9999013,0.00003149739,0.00001428468,0.00001519765,0.00001824912,0.00001951849],"domain_scores_gemma":[0.9998111,0.00002434165,0.00007507343,0.00002369398,0.00002449609,0.00004118316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001462289,0.00005761076,0.002800916,0.0002580406,0.00005114491,0.0009013854,0.00004366441,0.0001843242,0.989664,0.0002126854,0.00004621612,0.004317559],"study_design_scores_gemma":[0.00006639835,0.003745917,0.1009129,0.00005801405,0.0001726287,0.005618621,0.000290488,0.001508432,0.8826403,0.0009553865,0.004002693,0.00002821604],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9762837,0.02022254,0.001739229,0.0002389955,0.00003358792,0.00002713835,0.0001172094,0.00003147812,0.001306161],"genre_scores_gemma":[0.9922415,0.005655818,0.0008141877,0.00007555063,0.00002651528,0.00001069011,0.0001188929,0.000004106349,0.001052801],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0006752126,"threshold_uncertainty_score":0.002258778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0747733969022104,"score_gpt":0.377969597270671,"score_spread":0.3031962003684606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}