{"id":"W1970453602","doi":"10.1074/jbc.m211938200","title":"Interactions of a DNA-bound Transcriptional Activator with the TBP-TFIIA-TFIIB-Promoter Quaternary Complex","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Transcription factor II A; Transcription factor II B; TATA-binding protein; TATA box; TATA-Box Binding Protein; Transcription preinitiation complex; Promoter; Molecular biology; Cell biology; DNA-binding domain; Transcription (linguistics); Biology; Transcription factor; Chemistry; Genetics; DNA-binding protein; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000272027,0.0004374115,0.000385718,0.0002407891,0.0002984486,0.0005351714,0.0003838664,0.0003224276,0.001985108],"category_scores_gemma":[0.0003533926,0.0002360496,0.0003758282,0.0002346805,0.0002991343,0.0002437657,0.0003728959,0.0008425837,0.0006904639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000634796,"about_ca_system_score_gemma":0.000273671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007235501,"about_ca_topic_score_gemma":0.0005977369,"domain_scores_codex":[0.9997336,0.00004526011,0.00001256504,0.00007907697,0.00007811948,0.00005140693],"domain_scores_gemma":[0.9997936,0.00003364023,0.00003658004,0.00002658568,0.00002906226,0.00008056452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006521527,0.00001914785,0.0003135999,0.00002162473,0.000008600125,0.00002132782,0.00001895543,0.0001131671,0.9986273,0.0001857054,0.00002307004,0.0005823796],"study_design_scores_gemma":[0.00001429334,0.00009256766,0.002697914,0.000007048448,0.00001223129,0.0001512313,0.00002505662,0.002791628,0.991401,0.0001083401,0.002690291,0.000008396447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916627,0.0008046809,0.006260111,0.00006507415,0.00003000852,0.00001546946,0.0001017487,0.00006930015,0.0009908415],"genre_scores_gemma":[0.9925675,0.0002793215,0.004113524,0.00002755797,0.000007782949,0.00002046275,0.0006205795,0.0000324266,0.002330768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001985108,"threshold_uncertainty_score":0.006640851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03812808560148341,"score_gpt":0.2717665214379751,"score_spread":0.2336384358364917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}