{"id":"W1970453602","doi":"10.1074/jbc.m211938200","title":"Interactions of a DNA-bound Transcriptional Activator with the TBP-TFIIA-TFIIB-Promoter Quaternary Complex","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Transcription factor II A; Transcription factor II B; TATA-binding protein; TATA box; TATA-Box Binding Protein; Transcription preinitiation complex; Promoter; Molecular biology; Cell biology; DNA-binding domain; Transcription (linguistics); Biology; Transcription factor; Chemistry; Genetics; DNA-binding protein; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001932035,0.0001495426,0.0002100112,0.00001574803,0.0000595539,0.00001882678,0.0002729364,0.0001263053,0.0005061797],"category_scores_gemma":[0.00006348517,0.00007979399,0.0002002122,0.00006017771,0.0002336841,0.000008842888,0.0000258094,0.0002299225,0.00000252273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001734031,"about_ca_system_score_gemma":0.00009222513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002320398,"about_ca_topic_score_gemma":0.000001890657,"domain_scores_codex":[0.9991176,0.0000691943,0.0003306728,0.0001620368,0.0001475904,0.0001728785],"domain_scores_gemma":[0.9992209,0.00003171906,0.0002918497,0.0001755827,0.0001994193,0.00008053935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004187758,0.0001559141,0.002113466,0.00001308479,0.0001523472,0.0000102098,0.00003340983,0.00001086691,0.9955576,0.00001340084,0.001309894,0.0002110434],"study_design_scores_gemma":[0.000501344,0.0006368312,0.004121291,0.00003348546,0.0000285569,0.0005860415,0.0003185406,0.000006180723,0.9637935,0.00008705672,0.02976186,0.0001252772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973556,0.0002720709,0.0006379833,0.0003725593,0.00007748442,0.00004956292,0.00001929408,0.000002561509,0.001212903],"genre_scores_gemma":[0.9987813,0.00009220992,0.0003140517,0.0002132155,0.0002308571,0.000003780138,0.00002007694,0.000007884068,0.0003365968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03176406,"threshold_uncertainty_score":0.5542313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03812808560148341,"score_gpt":0.2717665214379751,"score_spread":0.2336384358364917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}