{"id":"W1970480941","doi":"10.1371/journal.ppat.1002982","title":"Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria","year":2012,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Malaria Research and Control","field":"Medicine","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; College of Medicine, Drexel University; School of Medicine, New York University; National Institutes of Health; York University; National Institute of Allergy and Infectious Diseases; Johns Hopkins University; Drexel University; Dana Foundation","keywords":"Plasmodium berghei; Cerebral Malaria; Blood–brain barrier; Histopathology; Plasmodium yoelii; Pathology; Biology; Evans Blue; Intravital microscopy; Immunology; Medicine; Malaria; Microcirculation; Central nervous system; Plasmodium falciparum; Internal medicine; Parasitemia; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003283882,0.0001646367,0.000309061,0.0001191706,0.00006921744,0.00002796324,0.0001381253,0.0001264796,0.002684141],"category_scores_gemma":[0.0005509892,0.0001352308,0.0001016477,0.0001590308,0.00006095652,0.0001508376,0.0001478495,0.0004297415,0.000185091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004635727,"about_ca_system_score_gemma":0.0000641942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001713978,"about_ca_topic_score_gemma":0.000002240634,"domain_scores_codex":[0.9982337,0.0001885811,0.0002380969,0.0002593728,0.0003299389,0.0007502502],"domain_scores_gemma":[0.9991859,0.0000946502,0.00003358124,0.0003074526,0.00003039236,0.0003480844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003226451,0.0009629326,0.1509286,0.00001257099,0.00006453573,0.0003276707,0.0003780766,2.983137e-7,0.8445162,0.002092757,0.0001083436,0.0002853633],"study_design_scores_gemma":[0.008502549,0.001154018,0.8233578,0.00007359734,0.00011023,0.0003241981,0.0007252193,0.0005820993,0.1634871,0.00003632259,0.001296793,0.0003500725],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901513,0.0009770914,0.0000143699,0.002442156,0.0000873902,0.0005725031,0.00001379724,0.00005969729,0.005681704],"genre_scores_gemma":[0.9972245,0.000005931136,0.0005910384,0.0009087459,0.0002700117,0.0001154464,0.00002029571,0.00002722786,0.0008368742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6810291,"threshold_uncertainty_score":0.9982275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03462845112557842,"score_gpt":0.2880860268600938,"score_spread":0.2534575757345153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}