{"id":"W1970480941","doi":"10.1371/journal.ppat.1002982","title":"Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria","year":2012,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Malaria Research and Control","field":"Medicine","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; College of Medicine, Drexel University; School of Medicine, New York University; National Institutes of Health; York University; National Institute of Allergy and Infectious Diseases; Johns Hopkins University; Drexel University; Dana Foundation","keywords":"Plasmodium berghei; Cerebral Malaria; Blood–brain barrier; Histopathology; Plasmodium yoelii; Pathology; Biology; Evans Blue; Intravital microscopy; Immunology; Medicine; Malaria; Microcirculation; Central nervous system; Plasmodium falciparum; Internal medicine; Parasitemia; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007855806,0.001482072,0.0006911225,0.001401968,0.0006429575,0.000582882,0.0006938881,0.0009144377,0.003711334],"category_scores_gemma":[0.0003959051,0.0004916994,0.0005707997,0.0006559073,0.001269746,0.000776307,0.0004372073,0.003525557,0.0008232367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007287536,"about_ca_system_score_gemma":0.0007407163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001800267,"about_ca_topic_score_gemma":0.002287268,"domain_scores_codex":[0.9992408,0.0001471834,0.00007680463,0.0001705429,0.0001808206,0.0001838602],"domain_scores_gemma":[0.9994646,0.00006286787,0.0001434959,0.0000987386,0.00008100071,0.0001493356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004317985,0.003677317,0.001013389,0.0003905739,0.00007512271,0.001078374,0.0003727356,0.0003109924,0.9800429,0.0008862713,0.0007674491,0.007066952],"study_design_scores_gemma":[0.0005895489,0.02118717,0.02001015,0.0001263635,0.0001719558,0.00285418,0.0003523081,0.002577608,0.9428139,0.0005533355,0.008695222,0.00006823428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821906,0.004155475,0.004168704,0.000528375,0.0005073511,0.000687742,0.001396977,0.0004801719,0.005884685],"genre_scores_gemma":[0.9752373,0.005185322,0.006432166,0.0004336732,0.0001710185,0.001981749,0.001852691,0.00009323561,0.008612776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003711334,"threshold_uncertainty_score":0.01241571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03462845112557842,"score_gpt":0.2880860268600938,"score_spread":0.2534575757345153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}