{"id":"W1970482120","doi":"10.1016/s0014-2999(03)02037-5","title":"Role of endothelin ETA receptors in sepsis-induced mortality, vascular leakage, and tissue injury in rats","year":2003,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Family Process Institute; Abbott Laboratories","keywords":"Sepsis; Creatine kinase; Lactate dehydrogenase; Endocrinology; Internal medicine; Creatinine; Endothelin receptor; Edema; Pulmonary edema; Kidney; Medicine; Chemistry; Receptor; Lung; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005985373,0.0009487302,0.0009615311,0.0007833257,0.0004548784,0.0004310918,0.0004818082,0.001007668,0.001521156],"category_scores_gemma":[0.0004965171,0.0007095328,0.0006200674,0.0003038186,0.001150878,0.001320954,0.0004065512,0.002289104,0.0003224113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005233907,"about_ca_system_score_gemma":0.0006343938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000726129,"about_ca_topic_score_gemma":0.0009097583,"domain_scores_codex":[0.9996583,0.00006867752,0.0000280686,0.00005513928,0.00005153962,0.0001382941],"domain_scores_gemma":[0.998917,0.0001090954,0.0002999803,0.0001376407,0.00008635469,0.0004499773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04835354,0.001581017,0.002226058,0.000149109,0.00008837275,0.0006366231,0.0001767702,0.000484128,0.938432,0.0005821601,0.0001357156,0.007154559],"study_design_scores_gemma":[0.0008691928,0.01400783,0.02353598,0.00002898958,0.0002349257,0.0005336759,0.0002531538,0.002176198,0.9569716,0.000554422,0.0007750452,0.00005907228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970955,0.001322382,0.0008098499,0.0001756325,0.00003723692,0.00001778148,0.0001625834,0.00004174412,0.0003373722],"genre_scores_gemma":[0.9950137,0.001113251,0.001253404,0.0001206753,0.00003538551,0.00007094647,0.0002505952,0.00001761654,0.002124521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001521156,"threshold_uncertainty_score":0.005088806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02133655324354237,"score_gpt":0.3219268564705245,"score_spread":0.3005903032269822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}