{"id":"W1970501943","doi":"10.1128/iai.74.4.2457-2461.2006","title":"Posttranslational Regulation of <i>Mycobacterium tuberculosis</i> Extracytoplasmic-Function Sigma Factor σ <sup>L</sup> and Roles in Virulence and in Global Regulation of Gene Expression","year":2006,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Biology; Sigma factor; Virulence; Mycobacterium tuberculosis; Virulence factor; Gene expression; Function (biology); Regulation of gene expression; Microbiology; Gene; Bacterial protein; Genetics; Tuberculosis; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373707,0.0002778471,0.000115291,0.0001495552,0.0001382077,0.0003979063,0.0001112097,0.0001700302,0.0007231509],"category_scores_gemma":[0.0001522264,0.00006847385,0.0002107964,0.00008499085,0.0003089961,0.0001960323,0.0001881695,0.0004240444,0.0004242269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000283167,"about_ca_system_score_gemma":0.000199975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005134384,"about_ca_topic_score_gemma":0.001112422,"domain_scores_codex":[0.9998839,0.00002249956,0.000009843776,0.00002394632,0.00002960658,0.00003017592],"domain_scores_gemma":[0.999754,0.00002734958,0.00009551588,0.00003632808,0.000048717,0.00003810932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005414583,0.000008808291,0.0009156571,0.00001399332,0.00000177948,0.00006185399,0.00001874672,0.00001948696,0.9976502,0.00005905145,0.00001859076,0.00117769],"study_design_scores_gemma":[0.000007286989,0.0001827906,0.023391,0.000005391413,0.00001193494,0.000312994,0.00009077323,0.0002726311,0.9740331,0.00008372308,0.001603775,0.000004475123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952247,0.001317089,0.00204382,0.0001630899,0.00001665819,0.000006942988,0.0001335622,0.00005484638,0.001039229],"genre_scores_gemma":[0.9971907,0.0003039866,0.00106724,0.00005187743,0.00001225848,0.00000504447,0.0002365999,0.00001388507,0.001118526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007231509,"threshold_uncertainty_score":0.002419174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01438476533667618,"score_gpt":0.2754289562846819,"score_spread":0.2610441909480058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}