{"id":"W1970571080","doi":"10.1016/j.chroma.2011.03.010","title":"Efficient purification of paclitaxel from yews using high-performance displacement chromatography technique","year":2011,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pfizer (Canada); Biotechnology Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Trifluoroacetic acid; Chemistry; Chromatography; Methanol; Solvent; Hexane; Elution; Paclitaxel; Chloroform; Aqueous solution; Acetic acid; Taxus; Acetonitrile; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003037871,0.0002018194,0.0005531112,0.0007092434,0.00005834871,0.000006807597,0.0001487122,0.0001134016,0.0002696971],"category_scores_gemma":[0.00000700628,0.000157769,0.0003815409,0.0006393395,0.0001694289,0.00008318019,0.00002266903,0.0002041902,0.000002356217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006781343,"about_ca_system_score_gemma":0.000128172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001691092,"about_ca_topic_score_gemma":0.000002325471,"domain_scores_codex":[0.9983652,0.00006463792,0.0008007779,0.0001695429,0.0003792896,0.0002205527],"domain_scores_gemma":[0.9984123,0.00003865965,0.0009037204,0.0002599382,0.0002290678,0.0001563657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001962046,0.003015438,0.2403408,0.0002643062,0.001430918,0.00007654116,0.001409599,0.00007507308,0.7490203,0.0001721685,0.0005600401,0.001672821],"study_design_scores_gemma":[0.004284226,0.002509169,0.4043296,0.0007275362,0.00120489,0.0002976324,0.0001687759,0.0003861761,0.5851079,0.0002010442,0.0005700752,0.0002130544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951078,0.001518575,0.00195976,0.00004976366,0.0003292066,0.0004759262,0.00002384636,0.00002203314,0.0005130388],"genre_scores_gemma":[0.9823675,0.0004632009,0.01691714,0.00005392024,0.000140451,0.00002249653,0.000008376432,0.00002231656,0.000004585003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1639888,"threshold_uncertainty_score":0.6433632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03016663391251069,"score_gpt":0.2873817177376819,"score_spread":0.2572150838251712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}