{"id":"W1970582321","doi":"10.1097/01.jto.0000283411.38367.97","title":"PD3-3-1: A phase Ib/randomized phase II, non-comparative, open label trial of paclitaxel and carboplatin with or without the anti-IGF-IR antibody CP-751,871 as first-line treatment for advanced non-small cell lung cancer (NSCLC)","year":2007,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Carboplatin; Internal medicine; Paclitaxel; Gastroenterology; Phases of clinical research; Pharmacokinetics; Oncology; Interim analysis; Clinical endpoint; Toxicity; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002380864,0.003066106,0.00344512,0.0009059858,0.0008457357,0.001921173,0.002132505,0.002513202,0.007478489],"category_scores_gemma":[0.001476855,0.00116638,0.00201242,0.000899821,0.002842172,0.002143082,0.0005785677,0.007094417,0.001651427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002021654,"about_ca_system_score_gemma":0.00293824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003217798,"about_ca_topic_score_gemma":0.0074445,"domain_scores_codex":[0.9994318,0.0002494854,0.00002336538,0.00009712205,0.00004724962,0.000150986],"domain_scores_gemma":[0.9991717,0.0001530279,0.0001274322,0.00005518413,0.00003317513,0.0004593492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9447278,0.01906348,0.0007833692,0.0004956269,0.0006966367,0.00007347792,0.0001063866,0.00110549,0.006348617,0.0003262139,0.002252634,0.02402015],"study_design_scores_gemma":[0.9426754,0.05463054,0.0008128279,0.000009864948,0.0001783039,0.00004821013,0.00002254273,0.0004102717,0.0005680265,0.0001794238,0.0004506673,0.00001388135],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819512,0.003116692,0.0008625357,0.001631636,0.0005485063,0.005423738,0.002752355,0.0004454034,0.003267907],"genre_scores_gemma":[0.9782069,0.00296906,0.002628382,0.002054817,0.0003724781,0.00554365,0.003453741,0.000101325,0.004669693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007478489,"threshold_uncertainty_score":0.02501798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05195269812214726,"score_gpt":0.4986769326342045,"score_spread":0.4467242345120573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}