{"id":"W1970585207","doi":"10.1002/jbmr.117","title":"<i>DMP1</i> C-terminal mutant mice recapture the human ARHR tooth phenotype","year":2010,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Child Health Clinician Scientist Program","keywords":"DMP1; Phenotype; Hypophosphatemia; Mutant; Dentinogenesis imperfecta; Hypophosphatemic Rickets; Biology; Mutation; Genetically modified mouse; PHEX; Fibroblast growth factor 23; Transgene; Molecular biology; Odontoblast; Genetics; Gene; Endocrinology; Internal medicine; Pathology; Rickets; Dentin; Anatomy; Medicine; Osteogenesis imperfecta; Calcium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001837799,0.0001114724,0.0003377913,0.0001551123,0.000312055,0.00006394625,0.0001023095,0.00009169348,0.00007600535],"category_scores_gemma":[0.0002971387,0.00005928054,0.000112958,0.0002022413,0.0003645667,0.0001127231,0.0001228351,0.001656655,0.00001260703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001995762,"about_ca_system_score_gemma":0.000113426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001302102,"about_ca_topic_score_gemma":0.0001671586,"domain_scores_codex":[0.9983563,0.00008107506,0.0003778803,0.0001324659,0.0007338941,0.0003184019],"domain_scores_gemma":[0.9988404,0.0001495828,0.0001243359,0.0001853292,0.0005089268,0.000191433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004866429,0.0001633443,0.002549696,0.00007565924,0.00008155399,0.0009377091,0.0006339464,8.041697e-8,0.9553585,0.0004888442,0.02887625,0.01034779],"study_design_scores_gemma":[0.0119356,0.009066011,0.1924315,0.001317009,0.0005674863,0.02660236,0.007052898,0.00005712745,0.08431314,0.008214383,0.6577139,0.0007284993],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821991,0.002928455,0.000003004274,0.006737973,0.0001670746,0.0001986431,0.000002203131,0.000004749887,0.007758811],"genre_scores_gemma":[0.9905932,0.0004479397,0.0003206166,0.0005032236,0.001201546,0.000004337767,0.000001198193,0.0000138003,0.006914147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8710454,"threshold_uncertainty_score":0.7197434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0520558327007957,"score_gpt":0.3747149591413186,"score_spread":0.3226591264405229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}