{"id":"W1970585207","doi":"10.1002/jbmr.117","title":"<i>DMP1</i> C-terminal mutant mice recapture the human ARHR tooth phenotype","year":2010,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Child Health Clinician Scientist Program","keywords":"DMP1; Phenotype; Hypophosphatemia; Mutant; Dentinogenesis imperfecta; Hypophosphatemic Rickets; Biology; Mutation; Genetically modified mouse; PHEX; Fibroblast growth factor 23; Transgene; Molecular biology; Odontoblast; Genetics; Gene; Endocrinology; Internal medicine; Pathology; Rickets; Dentin; Anatomy; Medicine; Osteogenesis imperfecta; Calcium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002168387,0.0007989481,0.0003245772,0.0006908643,0.000309687,0.0002784934,0.0005520894,0.0007272637,0.005607762],"category_scores_gemma":[0.0001123669,0.0002736181,0.0003911348,0.0002059463,0.0006233538,0.0002040073,0.0003835195,0.001448662,0.001465181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003822502,"about_ca_system_score_gemma":0.0002370261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008948505,"about_ca_topic_score_gemma":0.00135223,"domain_scores_codex":[0.9997219,0.00003795073,0.00004144382,0.00009023658,0.00006543699,0.00004292825],"domain_scores_gemma":[0.9998015,0.00002735213,0.00009042656,0.00001790027,0.00001018873,0.00005275818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008967623,0.00004232718,0.0002210048,0.00004136237,0.00000890228,0.0003219371,0.00001780615,0.00009003408,0.9976289,0.0004037573,0.0001078993,0.001026513],"study_design_scores_gemma":[0.00007792141,0.0002468841,0.00884137,0.00002820211,0.00004717743,0.005089119,0.00005109344,0.001873142,0.9707769,0.000229477,0.01272418,0.0000145731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706885,0.0008697995,0.01597773,0.0003646365,0.0001264284,0.000176782,0.005222957,0.0006957831,0.005877231],"genre_scores_gemma":[0.9672959,0.0006738573,0.01570873,0.0001922012,0.00003630242,0.0002551043,0.003597317,0.0003342319,0.01190631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005607762,"threshold_uncertainty_score":0.01875979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0520558327007957,"score_gpt":0.3747149591413186,"score_spread":0.3226591264405229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}