{"id":"W1970598278","doi":"10.1111/j.1471-4159.2009.06007.x","title":"HO‐1‐mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues","year":2009,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"McGill University; American Academy of Neurology","keywords":"Mechanism (biology); Autophagy; Chemistry; Cell biology; Neuroscience; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001777831,0.000293353,0.0002133559,0.000410876,0.000284532,0.0003049303,0.0001890096,0.0002203694,0.000564882],"category_scores_gemma":[0.00007015104,0.00008902573,0.0001189553,0.0001317319,0.0003802604,0.000330381,0.0002460087,0.0002952874,0.000132829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003484077,"about_ca_system_score_gemma":0.0002244069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003513021,"about_ca_topic_score_gemma":0.0005821918,"domain_scores_codex":[0.9999413,0.00000902047,0.000003414224,0.00001848827,0.00001506448,0.00001267493],"domain_scores_gemma":[0.9999496,0.000004089405,0.00002150921,0.000004872581,0.00000867259,0.0000113208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003630487,0.00003994414,0.002006973,0.0002016799,0.00002204985,0.0004050358,0.00008639214,0.00009989029,0.9780648,0.0009505523,0.0004801585,0.01727947],"study_design_scores_gemma":[0.00003379731,0.0007026088,0.07933347,0.00006099754,0.00006109569,0.00549667,0.0001885775,0.002389536,0.8900961,0.002013098,0.01959658,0.00002749369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9450865,0.04202162,0.008762917,0.0006313698,0.0001247653,0.0000549894,0.0002849967,0.0002293632,0.002803468],"genre_scores_gemma":[0.9838575,0.009877349,0.002508567,0.0001353681,0.00003927141,0.00003127269,0.0001312059,0.00001371071,0.003405783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000564882,"threshold_uncertainty_score":0.002527833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014529222367059,"score_gpt":0.2777343379099464,"score_spread":0.2675890456862758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}