{"id":"W1970620932","doi":"10.1186/1742-4690-8-s2-p53","title":"Impairment of viral replication capacity by nef alleles from HIV elite controllers","year":2011,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Virology; Viral replication; Biology; Infectivity; Plasmid; Allele; Gene; Virus; clone (Java method); ORFS; Recombinant DNA; Viremia; Genetics; Open reading frame; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003156174,0.0002421259,0.000189193,0.000341147,0.000222561,0.00044894,0.0002315012,0.0002872531,0.001981086],"category_scores_gemma":[0.0006943088,0.00007777537,0.0001388776,0.0001604922,0.0001371424,0.0002128535,0.0002256752,0.0004930712,0.0002537983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001941643,"about_ca_system_score_gemma":0.0001011817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005256319,"about_ca_topic_score_gemma":0.0003691007,"domain_scores_codex":[0.9998096,0.00002991307,0.00002081858,0.00003741224,0.00004814301,0.00005416536],"domain_scores_gemma":[0.9995597,0.000154103,0.00004941067,0.00008020511,0.00005273139,0.0001037097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007939916,0.0002386467,0.01097616,0.00004049114,0.00002050952,0.0008035214,0.0001127097,0.0001528449,0.9750166,0.000239898,0.0002316836,0.01137299],"study_design_scores_gemma":[0.0003184095,0.006512732,0.163929,0.00005671568,0.0001318848,0.02020015,0.0004069335,0.00675003,0.7909915,0.0005195553,0.01013199,0.00005108514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985268,0.0001817508,0.0005032715,0.00001036949,0.000005749802,0.00002082739,0.0002000211,0.00001505264,0.0005362889],"genre_scores_gemma":[0.9970407,0.0001368746,0.0008710332,0.00003027243,0.00001156373,0.00002806064,0.001059077,0.00001726869,0.0008051446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001981086,"threshold_uncertainty_score":0.006627381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878609294166059,"score_gpt":0.2311998303663874,"score_spread":0.2124137374247268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}