{"id":"W1970649495","doi":"10.1081/ncn-100001435","title":"SYNTHESIS OF 1-(2-DEOXY-β-<scp>D</scp>- RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENE THYMIDINE MIMICS,<sup>*</sup>SOME RELATED α-ANOMERS, AND THEIR EVALUATION AS ANTIVIRAL AND ANTICANCER AGENTS","year":2001,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Anomer; Chemistry; Stereochemistry; Cytotoxicity; Nucleoside; Thymidine; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001003389,0.0003439385,0.0002047486,0.00009342471,0.00009804506,0.0001581407,0.0001878151,0.0001931566,0.0008452756],"category_scores_gemma":[0.00009596167,0.0001015245,0.0001513378,0.0001572358,0.00007739368,0.0001618745,0.00009620126,0.0002023599,0.0004026808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001862698,"about_ca_system_score_gemma":0.0001832114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004768194,"about_ca_topic_score_gemma":0.0007774449,"domain_scores_codex":[0.9999306,0.00001454552,0.000006823847,0.0000172011,0.00001450985,0.00001634164],"domain_scores_gemma":[0.9999409,0.000005100818,0.00001902449,0.000006171343,0.000009828127,0.00001896218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000688338,0.00001412333,0.00009107959,0.00004592532,0.00000344502,0.00004389309,0.00001101797,0.0001857244,0.9969015,0.0001196458,0.00003358254,0.002481282],"study_design_scores_gemma":[0.00001163618,0.0005291218,0.0007860199,0.000004931252,0.00001397399,0.0002712547,0.000009454545,0.0004005415,0.9931567,0.00001846848,0.004791649,0.000006205393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973349,0.0051098,0.01568345,0.00006937912,0.00005724282,0.0001214401,0.00073288,0.0001634938,0.004713384],"genre_scores_gemma":[0.978369,0.002176415,0.01560231,0.00005899472,0.00001355245,0.00006699669,0.0008915102,0.00002601876,0.002795291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008452756,"threshold_uncertainty_score":0.002827764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02210800549271585,"score_gpt":0.2548201975568576,"score_spread":0.2327121920641418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}