{"id":"W1970649495","doi":"10.1081/ncn-100001435","title":"SYNTHESIS OF 1-(2-DEOXY-β-<scp>D</scp>- RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENE THYMIDINE MIMICS,<sup>*</sup>SOME RELATED α-ANOMERS, AND THEIR EVALUATION AS ANTIVIRAL AND ANTICANCER AGENTS","year":2001,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Anomer; Chemistry; Stereochemistry; Cytotoxicity; Nucleoside; Thymidine; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001641323,0.0008907506,0.001276432,0.0003050487,0.0004742171,0.0002180587,0.0005985451,0.0007264329,0.001787388],"category_scores_gemma":[0.003299828,0.0007306437,0.0003516485,0.0005565241,0.0009792052,0.0009346056,0.0003541835,0.0004932989,0.000111114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000210527,"about_ca_system_score_gemma":0.0001075976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00017659,"about_ca_topic_score_gemma":0.00001064665,"domain_scores_codex":[0.9949989,0.0003547384,0.001408215,0.001359878,0.0009343286,0.0009439852],"domain_scores_gemma":[0.9960285,0.001559487,0.0007582272,0.0008903369,0.0004040471,0.0003593661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000353028,0.0008182556,0.07006162,0.0004267162,0.001039709,0.0000462223,0.002667766,0.0003097323,0.7288651,0.002774896,0.0007222269,0.1919147],"study_design_scores_gemma":[0.006275499,0.0006950137,0.1975542,0.001995488,0.002411006,0.0004064717,0.01059815,0.1321079,0.6141857,0.01782408,0.01390807,0.002038361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860157,0.00233329,0.00001061184,0.0005333701,0.0001488324,0.0005841026,0.0001339972,0.0003007588,0.009939303],"genre_scores_gemma":[0.9933962,0.004998403,0.0005758543,0.0002866398,0.0002349434,0.00006673262,0.00008599665,0.0001452404,0.0002100227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1898763,"threshold_uncertainty_score":0.9995145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02210800549271585,"score_gpt":0.2548201975568576,"score_spread":0.2327121920641418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}