{"id":"W1970658737","doi":"10.1002/1521-4141(200206)32:6<1802::aid-immu1802>3.0.co;2-c","title":"Differential activation of human and guinea pig complement by pentameric and hexameric IgM","year":2002,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Random hexamer; Pentamer; Biology; Complement system; Molecular biology; Classical complement pathway; Guinea pig; Antibody; Biochemistry; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001521786,0.00009589482,0.0002937781,0.000128505,0.00006879478,0.000009248438,0.00008381997,0.00001441619,0.001156815],"category_scores_gemma":[0.00002971739,0.00007135905,0.00004866595,0.00006634297,0.0002829341,0.00004608673,0.00008971214,0.0002330086,0.000007898249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000134243,"about_ca_system_score_gemma":0.000006234865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002376294,"about_ca_topic_score_gemma":2.832697e-7,"domain_scores_codex":[0.9989696,0.0002310253,0.000390294,0.00009261254,0.000167422,0.0001490687],"domain_scores_gemma":[0.9994435,0.00005018517,0.0002603444,0.00008174542,0.00009118191,0.00007304375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003696558,0.0002479801,0.01136426,0.00005146592,0.0002844924,0.00007886631,0.0004544182,1.900218e-7,0.9203637,0.0001068002,0.005759468,0.06091866],"study_design_scores_gemma":[0.007526907,0.01318502,0.8668993,0.0003001899,0.0001597495,0.002169337,0.0006645119,0.0001348184,0.04577539,0.00004875206,0.06287878,0.0002572729],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937788,0.002561362,0.0001249663,0.001620464,0.00005562575,0.00006653168,0.000004577634,0.000003287901,0.001784363],"genre_scores_gemma":[0.9970503,0.001650079,0.000166765,0.0001172107,0.00009233208,2.621965e-7,0.000007802262,0.00001219436,0.000903014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8745884,"threshold_uncertainty_score":0.9997563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03746885017872686,"score_gpt":0.2892303612032197,"score_spread":0.2517615110244928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}