{"id":"W1970715182","doi":"10.1007/s00280-005-1023-2","title":"Identification of biliary metabolites of ifosfamide using 31P magnetic resonance spectroscopy and mass spectrometry","year":2005,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"Ifosfamide; Chemistry; In vivo; Mass spectrometry; Glutathione; Metabolite; Magnetic resonance imaging; Pharmacology; Drug metabolism; Chromatography; Metabolism; Biochemistry; Medicine; Internal medicine; Biology; Chemotherapy; Enzyme; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001999833,0.0001554615,0.0004070649,0.0001733026,0.000035669,0.00000557484,0.00006204558,0.0001099988,0.0006281615],"category_scores_gemma":[0.00001217353,0.0001551631,0.00004844112,0.0002991945,0.0002864572,0.00009501811,0.00001162668,0.0001492094,6.948307e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009568588,"about_ca_system_score_gemma":0.00009989367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002666101,"about_ca_topic_score_gemma":0.000002988443,"domain_scores_codex":[0.9989315,0.00004949119,0.0004053263,0.0002896501,0.000133333,0.0001906949],"domain_scores_gemma":[0.9993959,0.00007166823,0.0002229013,0.0001454207,0.00008512173,0.00007896512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003913786,0.00009199436,0.01204118,0.0001884745,0.00006820322,9.760607e-7,0.0004732097,0.000004654421,0.9712971,0.00003454529,0.0001066523,0.01530166],"study_design_scores_gemma":[0.002732588,0.000149693,0.02001053,0.00004429573,0.0001627689,0.00002167967,0.0000483127,0.001811271,0.9734223,0.0002816975,0.001200198,0.0001146226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.956541,0.04066639,0.000388859,0.001844872,0.0001093696,0.0003421845,0.00002431126,0.00001988329,0.00006314118],"genre_scores_gemma":[0.9746661,0.01697714,0.006764032,0.001068651,0.0003476243,0.00001140045,0.00000326348,0.00002955895,0.0001322792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02368926,"threshold_uncertainty_score":0.6877928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01539760505379197,"score_gpt":0.3220975698028973,"score_spread":0.3066999647491054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}