{"id":"W1970734671","doi":"10.3899/jrheum.141163","title":"Levels in Plasma of the Serine Proteases and Associated Proteins of the Lectin Pathway Are Altered in Patients with Systemic Lupus Erythematosus","year":2015,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novo Nordisk Fonden; Aarhus Universitet","keywords":"Proteases; Medicine; Serine; Lectin; Immunology; MASP1; Systemic lupus erythematosus; Lupus erythematosus; Serine protease; Internal medicine; Biochemistry; Disease; Biology; Enzyme; Antibody; Protease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008397555,0.0001458241,0.0006149369,0.0001107073,0.0000549567,0.000003391446,0.0004686152,0.00009740762,0.00001363055],"category_scores_gemma":[0.0007138904,0.00006565054,0.00006072104,0.0002321666,0.0002702464,0.00005375088,0.0001765765,0.0002856542,0.000001139336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007913053,"about_ca_system_score_gemma":0.0002211463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003447152,"about_ca_topic_score_gemma":0.001216021,"domain_scores_codex":[0.9971407,0.001600455,0.0008376954,0.00009583795,0.0001129492,0.0002123779],"domain_scores_gemma":[0.9973111,0.000311731,0.001820389,0.0002927239,0.000245759,0.00001834124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009363862,0.0002703616,0.9948429,0.0001346701,0.0001583985,0.000001043177,0.001592689,0.00007727525,0.001742369,0.00004305948,0.0001596197,0.00004122972],"study_design_scores_gemma":[0.0107114,0.0006693875,0.9721038,0.003468929,0.00006805448,0.003100556,0.003036501,0.000008884471,0.006432871,0.0002464108,0.00002913194,0.0001240126],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975051,0.000756062,0.000003505078,0.0002114064,0.0004431267,0.001023897,0.00004370276,0.000004077601,0.000009064138],"genre_scores_gemma":[0.9999049,0.000008279969,0.00000559004,0.000007833305,0.000001458911,0.0000166327,0.000001343385,0.0000109053,0.00004300226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02273904,"threshold_uncertainty_score":0.2677151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01802753157850593,"score_gpt":0.2168241556780351,"score_spread":0.1987966240995291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}