{"id":"W1970776132","doi":"10.1002/1521-4141(200006)30:6<1748::aid-immu1748>3.0.co;2-j","title":"Binding of Mycoplasma arthritidis-derived mitogen to human MHC class II molecules via its N terminus is modulated by invariant chain expression and its C terminus is required for T cell activation","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Medical Research Council; Arthritis Society","keywords":"CD74; Biology; MHC restriction; MHC class II; MHC class I; Major histocompatibility complex; Antigen presentation; Cell biology; T-cell receptor; T cell; Peptide; Molecular biology; Antigen; Immune system; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001022853,0.0002250436,0.0001539898,0.00007990805,0.0001237708,0.0002133403,0.00008548065,0.0001531867,0.0009120479],"category_scores_gemma":[0.0001987313,0.000104902,0.0001302887,0.00005656295,0.0001397271,0.0001312827,0.0001589742,0.0002896998,0.0004028245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001838691,"about_ca_system_score_gemma":0.0001308375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003002755,"about_ca_topic_score_gemma":0.0003619016,"domain_scores_codex":[0.999895,0.0000228108,0.000008008947,0.00001471583,0.00002300449,0.00003647906],"domain_scores_gemma":[0.999874,0.00002942077,0.00003313288,0.00001276968,0.00001420356,0.00003652323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006397602,0.000006883654,0.0001303822,0.00001016464,7.35626e-7,0.00002674186,0.00000555487,0.000009196627,0.9995627,0.00002093767,0.000004794693,0.00015799],"study_design_scores_gemma":[0.00003542176,0.0004626052,0.0265807,0.00001214333,0.00001383255,0.0006844082,0.00006934734,0.001011044,0.9692119,0.000103369,0.001808443,0.000006631045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984303,0.0005484031,0.0005172074,0.00002065457,0.000006591732,0.000006299479,0.00004970045,0.00000788763,0.0004130155],"genre_scores_gemma":[0.9983937,0.0003037131,0.0005392736,0.00002262695,0.000006567458,0.0000100788,0.0002134054,0.000005488666,0.000505157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009120479,"threshold_uncertainty_score":0.003051102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01717257904972132,"score_gpt":0.2498353963489824,"score_spread":0.2326628172992611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}