{"id":"W1970816552","doi":"10.1038/hr.2009.70","title":"Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis","year":2009,"lang":"en","type":"article","venue":"Hypertension Research","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Key Research and Development Program of China; Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Quantitative trait locus; Epistasis; Congenic; Biology; Genetics; Gene; Candidate gene; Chromosome; Positional cloning; Chromosomal region; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001617325,0.0001505547,0.0003861818,0.0001832041,0.0003729439,0.00004254626,0.0001349807,0.0001294878,0.0000114914],"category_scores_gemma":[0.001820501,0.0001317486,0.0001380292,0.0004374127,0.0001453705,0.000003770881,0.0001022568,0.0002061665,0.000006788955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002696821,"about_ca_system_score_gemma":0.0000617947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005654661,"about_ca_topic_score_gemma":0.0001197842,"domain_scores_codex":[0.9978045,0.0005939205,0.0002880385,0.0005345173,0.0002635813,0.0005153925],"domain_scores_gemma":[0.9986539,0.0002298218,0.00008836446,0.0003433443,0.0005235461,0.0001610371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001146443,0.0001486091,0.03769062,0.000017977,0.0007577771,0.00004848619,0.0003648808,0.0009772494,0.9344324,0.001046939,0.005482657,0.01891772],"study_design_scores_gemma":[0.00150709,0.001331111,0.9280776,0.00002491484,0.0004903367,0.00003466454,0.003094895,0.03314994,0.02146928,0.003424599,0.006657658,0.0007379216],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948874,0.001683922,0.001686018,0.0008860057,0.00004029563,0.0001734215,0.0000824692,0.00001183017,0.0005486892],"genre_scores_gemma":[0.9914871,0.0006024555,0.006870957,0.0002775115,0.0001093033,0.00001491702,0.0004265239,0.00001361376,0.0001976044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9129632,"threshold_uncertainty_score":0.5372551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07936431505168777,"score_gpt":0.3638872622724107,"score_spread":0.284522947220723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}