{"id":"W1970864797","doi":"10.1002/jcb.20200","title":"Effect of overexpression and nuclear translocation of constitutively active PKB‐α on cellular survival and proliferation in HepG2 cells","year":2004,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Protein kinase B; Phosphorylation; Transfection; Cell biology; Cell growth; Biology; Growth factor; Kinase; PI3K/AKT/mTOR pathway; Cancer research; Signal transduction; Cell culture; Chemistry; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004164955,0.0001617731,0.0002962719,0.00005997368,0.0000276098,0.000009584242,0.0001041204,0.000218895,0.00000481405],"category_scores_gemma":[0.00007206676,0.0001448671,0.00008051916,0.00006624062,0.0001909906,0.00001118863,0.00002668092,0.000174007,1.791314e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004014397,"about_ca_system_score_gemma":0.0001391956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007225584,"about_ca_topic_score_gemma":6.178564e-7,"domain_scores_codex":[0.9989606,0.00008876629,0.0004035272,0.0002022953,0.0002264076,0.0001184614],"domain_scores_gemma":[0.9992018,0.0000353814,0.0004219305,0.0001447253,0.0001245164,0.00007163327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001292833,0.0001031291,0.000200399,0.0002662975,0.00004870549,0.000006158898,0.0001230744,0.0002552136,0.9969969,0.00003445554,0.00000968514,0.0006631574],"study_design_scores_gemma":[0.002261667,0.001216684,0.00006875599,0.0004914545,0.00003447445,0.0000171448,0.00007647668,0.00002400017,0.9956167,0.00003462695,0.00003705879,0.0001209402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979451,0.001108317,0.000514685,0.0000248991,0.00009096084,0.0001387271,0.0000216079,0.000001705009,0.000153958],"genre_scores_gemma":[0.9993412,0.0002244463,0.0002593126,0.000009691862,0.0001272228,0.000001729752,0.00001349231,0.00001514645,0.000007729923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001396088,"threshold_uncertainty_score":0.5907507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004426051535076044,"score_gpt":0.2318282032046609,"score_spread":0.2274021516695849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}