{"id":"W1970866846","doi":"10.1016/j.freeradbiomed.2011.10.150","title":"Estrogen Receptors and the Mitochondrial Antioxidant Enzyme Manganese Superoxide Dismutase Are Two Key Players in the Cellular Activities of Phytoestrogens","year":2011,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"","keywords":"Ovariectomized rat; Superoxide dismutase; Glutathione peroxidase; Oxidative stress; Endocrinology; Internal medicine; Antioxidant; Glutathione; Estrogen; Glutathione reductase; Estrogen receptor; Biology; Mitochondrion; Free-radical theory of aging; Dismutase; Chemistry; Biochemistry; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002863063,0.0002935673,0.0003227511,0.0002032116,0.0001572074,0.0004940275,0.000275454,0.0004432068,0.0009794038],"category_scores_gemma":[0.000360658,0.0002418387,0.000238009,0.0001473056,0.0002515184,0.0003525796,0.0002615163,0.0003708788,0.0002632303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004376084,"about_ca_system_score_gemma":0.0002957354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007600558,"about_ca_topic_score_gemma":0.001482161,"domain_scores_codex":[0.999799,0.00003499644,0.00001196843,0.00004375739,0.00007393479,0.00003654209],"domain_scores_gemma":[0.9997724,0.00004114691,0.00008219283,0.00001990245,0.000045753,0.00003859368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001072194,0.00008425341,0.004337381,0.0001772918,0.00005276076,0.0002256545,0.00008061752,0.0001233541,0.9760361,0.002481169,0.0003094435,0.01501979],"study_design_scores_gemma":[0.0002118905,0.0009572261,0.08097439,0.00005687428,0.0001822596,0.001530467,0.0003239797,0.001203164,0.8885549,0.003363381,0.02260417,0.0000373208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9256977,0.04560623,0.02114274,0.002792366,0.0002330715,0.00005052966,0.0007125753,0.0001985997,0.003566215],"genre_scores_gemma":[0.983439,0.007844481,0.002937394,0.0001840613,0.00007823143,0.0000209296,0.0004111545,0.000009433673,0.005075359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009794038,"threshold_uncertainty_score":0.003276408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300320838076271,"score_gpt":0.2428242843296776,"score_spread":0.2298210759489149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}