{"id":"W1970886233","doi":"10.4161/epi.4.6.9767","title":"Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation","year":2009,"lang":"en","type":"article","venue":"Epigenetics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Acetylation; SAP30; Biology; Acetylcarnitine; Histone; Histone Acetyltransferases; Mitochondrion; HDAC4; Histone acetyltransferase; Biochemistry; HDAC11; Histone H2A; Acetyl-CoA; Histone deacetylase 5; Histone methyltransferase; Cell biology; Carnitine; DNA; Gene; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001268907,0.0002278946,0.0002176409,0.0001681947,0.0002057707,0.0003163163,0.0002179179,0.0002443402,0.001938083],"category_scores_gemma":[0.0001926589,0.0001514992,0.0001946715,0.0002184528,0.0002607633,0.000278521,0.0002845206,0.0002942042,0.0008263817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004147597,"about_ca_system_score_gemma":0.0004016632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148567,"about_ca_topic_score_gemma":0.002168731,"domain_scores_codex":[0.9998935,0.00001411375,0.000009337641,0.00003523149,0.00002757972,0.00002027684],"domain_scores_gemma":[0.9998677,0.00001204619,0.00003545414,0.00002781119,0.00002968756,0.00002733256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001684917,0.000006723471,0.0005102382,0.00003909881,0.000008529591,0.00008269438,0.00001313511,0.0000458227,0.9969618,0.000327803,0.00003491803,0.001800669],"study_design_scores_gemma":[0.00001961409,0.0001510598,0.005299439,0.000008584497,0.0000195615,0.0004479849,0.00002904511,0.0003102692,0.9877537,0.0002253733,0.005728623,0.000006648912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714217,0.008725048,0.01366714,0.0005808182,0.0001800391,0.00002292254,0.0007557967,0.0002663939,0.004380081],"genre_scores_gemma":[0.9913607,0.002484095,0.002479509,0.00005221124,0.00002235573,0.000006643855,0.0004602409,0.00001879253,0.003115471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001938083,"threshold_uncertainty_score":0.006483495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01332563732866563,"score_gpt":0.2675649592724963,"score_spread":0.2542393219438307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}