{"id":"W1970886233","doi":"10.4161/epi.4.6.9767","title":"Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation","year":2009,"lang":"en","type":"article","venue":"Epigenetics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Acetylation; SAP30; Biology; Acetylcarnitine; Histone; Histone Acetyltransferases; Mitochondrion; HDAC4; Histone acetyltransferase; Biochemistry; HDAC11; Histone H2A; Acetyl-CoA; Histone deacetylase 5; Histone methyltransferase; Cell biology; Carnitine; DNA; Gene; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001210281,0.0002158041,0.0002056762,0.00005560158,0.0001842016,0.00003412397,0.0001991192,0.0003132196,0.0000962453],"category_scores_gemma":[0.0002470546,0.0002240569,0.0001687381,0.00008398683,0.0000701823,0.000005308813,0.00004467861,0.0001057208,0.00004361832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002422764,"about_ca_system_score_gemma":0.00004762342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001792478,"about_ca_topic_score_gemma":0.00001324703,"domain_scores_codex":[0.9986977,0.00007417616,0.0003072645,0.0004597162,0.0001293922,0.0003317276],"domain_scores_gemma":[0.999173,0.00002007816,0.0001305177,0.0004144024,0.0001438439,0.0001181372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004603728,0.00008819324,0.0000467236,0.00001138141,0.00002222487,0.000001195071,0.0001106736,0.0001240288,0.9698544,0.001412307,0.02013107,0.007737505],"study_design_scores_gemma":[0.002267264,0.002967005,0.0006205514,0.00001051322,0.00006138952,0.0000318165,0.0000929942,0.0002630803,0.1940537,0.0009596384,0.7982199,0.0004520897],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9311489,0.00120055,0.05778702,0.002564769,0.00275753,0.001331428,0.00007672027,0.0001164918,0.003016551],"genre_scores_gemma":[0.9444852,0.0004080707,0.04113076,0.002437805,0.00481061,0.00005281277,0.0008281413,0.00008724962,0.005759342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7780889,"threshold_uncertainty_score":0.9136777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01332563732866563,"score_gpt":0.2675649592724963,"score_spread":0.2542393219438307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}