{"id":"W1970920336","doi":"10.1038/labinvest.2009.131","title":"Detergent-resistant microdomains mediate activation of host cell signaling in response to attaching–effacing bacteria","year":2009,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"Lipid raft; Biology; Citrobacter rodentium; Cell biology; Secretion; Signal transduction; Microbiology; Pathogen; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007408136,0.0001301406,0.0001396926,0.0001269011,0.00006561213,0.00001987887,0.0001210105,0.00009253531,0.000003415082],"category_scores_gemma":[0.000745918,0.000138344,0.00002717453,0.0004014508,0.00004940938,0.00001531967,0.00004781525,0.00009572291,0.000002816616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006129441,"about_ca_system_score_gemma":0.0001939172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000154366,"about_ca_topic_score_gemma":0.00004209153,"domain_scores_codex":[0.9987048,0.000354084,0.0002923871,0.0002641357,0.0001742325,0.0002103937],"domain_scores_gemma":[0.9993358,0.00004558201,0.0001223784,0.0002127712,0.0001811802,0.0001022348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005463407,0.000029648,0.005298243,0.0000249149,0.000007552801,0.000001467134,0.0005837588,0.0002046224,0.9931467,0.000009775882,0.00008177045,0.00006524885],"study_design_scores_gemma":[0.000348716,0.0003731387,0.1102796,0.00005278198,0.000003608095,9.010306e-8,0.0001354448,0.00002513098,0.888001,0.00002555342,0.0006318279,0.0001230917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989972,0.00009154255,0.0001724008,0.0003798101,0.00004494959,0.0002493523,0.0000263112,0.00001105785,0.00002739898],"genre_scores_gemma":[0.9962866,0.00001680264,0.003072097,0.0004706631,0.00006160256,0.00001884943,0.0000385616,0.00001328544,0.00002150499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1051457,"threshold_uncertainty_score":0.5641503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089131953083756,"score_gpt":0.2630762408931079,"score_spread":0.2521849213622703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}