{"id":"W1970920336","doi":"10.1038/labinvest.2009.131","title":"Detergent-resistant microdomains mediate activation of host cell signaling in response to attaching–effacing bacteria","year":2009,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"Lipid raft; Biology; Citrobacter rodentium; Cell biology; Secretion; Signal transduction; Microbiology; Pathogen; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002498804,0.0005288974,0.0003000895,0.0003108768,0.0003703592,0.0006038207,0.0003056909,0.0004572752,0.002077993],"category_scores_gemma":[0.0002966014,0.0002974714,0.0005095461,0.000192218,0.0003483412,0.0004821736,0.0005603979,0.001182938,0.0007619279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005866376,"about_ca_system_score_gemma":0.0001830726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003890755,"about_ca_topic_score_gemma":0.0006414904,"domain_scores_codex":[0.9997086,0.00004887188,0.00002165934,0.00004011662,0.00005396989,0.0001266688],"domain_scores_gemma":[0.9997485,0.00007774332,0.00004369189,0.00003600519,0.00003116215,0.00006291339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001647553,0.00001799056,0.00006118778,0.00001237346,0.000001787409,0.00002520186,0.000009817493,0.00001255175,0.9994296,0.00007973071,0.00001037459,0.000174507],"study_design_scores_gemma":[0.00002625791,0.00009193582,0.006096072,0.000005156647,0.000006798173,0.0001171227,0.00005947581,0.0004543618,0.9925156,0.00008258989,0.0005402116,0.000004348939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945274,0.0007514395,0.002113772,0.000122258,0.00002808035,0.00004295239,0.000355246,0.000030699,0.002028032],"genre_scores_gemma":[0.9946505,0.0004196157,0.002052692,0.0000734569,0.00001853238,0.00005164515,0.0007388105,0.0000181465,0.001976617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002077993,"threshold_uncertainty_score":0.006951571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089131953083756,"score_gpt":0.2630762408931079,"score_spread":0.2521849213622703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}