{"id":"W1971013026","doi":"10.1107/s1744309112011487","title":"The structure of an orthorhombic crystal form of a `forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag","year":2012,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology and Crystallization Communications","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Wellcome Trust","keywords":"Orthorhombic crystal system; Crystal structure; Peroxiredoxin; Linker; Crystallography; Peroxidase; Thiol; Chemistry; Molecular replacement; Crystal (programming language); Stereochemistry; Enzyme; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003083742,0.0003167822,0.0005180509,0.0001978334,0.0004674777,0.0007885924,0.0009970678,0.000881565,0.002306019],"category_scores_gemma":[0.0003918337,0.0002902336,0.0002204825,0.0005558268,0.000469751,0.0004680085,0.0002500201,0.002533629,0.0004157531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007363166,"about_ca_system_score_gemma":0.0007659091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005362706,"about_ca_topic_score_gemma":0.003556689,"domain_scores_codex":[0.9998251,0.00001467246,0.000005404831,0.00003813235,0.00008416519,0.00003266975],"domain_scores_gemma":[0.9997535,0.00005434694,0.00004080853,0.00002039247,0.00005456474,0.00007642491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001330809,0.0003831329,0.003434061,0.0005460792,0.0001217761,0.002439302,0.0008006977,0.003468705,0.9385819,0.004724971,0.02189717,0.02227142],"study_design_scores_gemma":[0.00198674,0.002342846,0.127201,0.0001642095,0.0004109118,0.007505831,0.001586276,0.1481671,0.5685949,0.003757363,0.1378436,0.0004392032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793676,0.002797211,0.005827654,0.00162635,0.0004652108,0.00004093269,0.002024942,0.001103396,0.006746694],"genre_scores_gemma":[0.974775,0.0018464,0.01117295,0.0002953252,0.00004342085,0.0000443868,0.005276776,0.0002045759,0.006341175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005362706,"threshold_uncertainty_score":0.01066303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01400125037592264,"score_gpt":0.2635372440684173,"score_spread":0.2495359936924947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}