{"id":"W1971049244","doi":"10.1111/j.1751-7915.2009.00142.x","title":"Nature versus nurture in two highly enantioselective esterases from <i>Bacillus cereus</i> and <i>Thermoanaerobacter tengcongensis</i>","year":2009,"lang":"en","type":"article","venue":"Microbial Biotechnology","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Bacillus cereus; Enantioselective synthesis; Thermophile; Nature versus nurture; Biology; Microbiology; Bacillus (shape); Bacteria; Chemistry; Computational biology; Biochemistry; Genetics; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279503,0.0002631033,0.0002143332,0.0001440174,0.00007857212,0.0004071095,0.00023699,0.000224145,0.0004180819],"category_scores_gemma":[0.0002388751,0.0001265371,0.0003192663,0.0002665056,0.0001628559,0.000179064,0.0002198018,0.0003698062,0.0002948621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002598701,"about_ca_system_score_gemma":0.0002455811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001918816,"about_ca_topic_score_gemma":0.00240705,"domain_scores_codex":[0.9998454,0.00002077559,0.00001864659,0.00003521148,0.00005521122,0.00002482283],"domain_scores_gemma":[0.9998754,0.00001411586,0.00005833956,0.00001266987,0.0000212315,0.00001821637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111958,0.00001819224,0.001346889,0.00003379754,0.00000923767,0.0001125978,0.00004533462,0.0001960594,0.9955178,0.00009866773,0.00002226798,0.002487309],"study_design_scores_gemma":[0.0000155642,0.00024483,0.0168954,0.00001233279,0.00004111139,0.001000078,0.0001485169,0.00177022,0.9756477,0.00009881154,0.004109687,0.00001574818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969822,0.000447223,0.001434934,0.00007937778,0.000009826345,0.000006784457,0.0002730281,0.00003039553,0.0007361425],"genre_scores_gemma":[0.9953322,0.0002269327,0.002467838,0.00004200837,0.000002747689,0.000007157736,0.0008686185,0.00003066597,0.00102201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001918816,"threshold_uncertainty_score":0.003815234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003821973047307367,"score_gpt":0.2280838478697658,"score_spread":0.2242618748224585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}