{"id":"W1971049244","doi":"10.1111/j.1751-7915.2009.00142.x","title":"Nature versus nurture in two highly enantioselective esterases from <i>Bacillus cereus</i> and <i>Thermoanaerobacter tengcongensis</i>","year":2009,"lang":"en","type":"article","venue":"Microbial Biotechnology","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Bacillus cereus; Enantioselective synthesis; Thermophile; Nature versus nurture; Biology; Microbiology; Bacillus (shape); Bacteria; Chemistry; Computational biology; Biochemistry; Genetics; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006168421,0.0002391293,0.0002531672,0.0001226567,0.00006161221,0.00003000443,0.0002034007,0.0008186969,0.00001064764],"category_scores_gemma":[0.0000843674,0.0002220791,0.00006758017,0.0002495673,0.0001361909,0.00001012415,0.00009014654,0.0003785494,0.000007042825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003301938,"about_ca_system_score_gemma":0.00003499032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007201415,"about_ca_topic_score_gemma":0.0008651335,"domain_scores_codex":[0.9987576,0.00005172394,0.0002243388,0.000614193,0.0000534073,0.0002987339],"domain_scores_gemma":[0.9994146,0.00001625977,0.00008525539,0.000383757,0.00005846656,0.00004167366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002603228,0.00006798517,0.0002657613,0.00000224903,0.00004408509,0.00000807219,0.00003037826,0.000005380799,0.9919959,0.0001567679,0.001553233,0.005609832],"study_design_scores_gemma":[0.001916779,0.0003257204,0.001682187,0.00001599102,0.00002925116,0.00001581143,0.00003679725,0.000006475132,0.9588509,0.00008345174,0.0367747,0.0002618993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947229,0.002929352,0.0001173453,0.00152853,0.0002510579,0.000186558,0.0000841798,0.00004322871,0.0001368578],"genre_scores_gemma":[0.9966787,0.0006720119,0.000421574,0.001378716,0.0001577733,0.000005539782,0.0005779359,0.00001876885,0.00008899032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03522146,"threshold_uncertainty_score":0.9056125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003821973047307367,"score_gpt":0.2280838478697658,"score_spread":0.2242618748224585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}