{"id":"W1971084572","doi":"10.1038/nature09413","title":"Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1097,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Pannexin; Cell biology; Apoptosis; Caspase; Biology; Effector; Programmed cell death; Biochemistry; Intracellular; Gap junction; Connexin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003743384,0.0002326159,0.0002978875,0.0002407629,0.0003752677,0.0006947754,0.0002598077,0.0006770552,0.0012096],"category_scores_gemma":[0.0003492356,0.0002291119,0.000228899,0.0001511268,0.0004454492,0.002223385,0.0004643234,0.001019786,0.0003355343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007263657,"about_ca_system_score_gemma":0.0001356633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001418842,"about_ca_topic_score_gemma":0.0002807455,"domain_scores_codex":[0.9998065,0.00002402154,0.00001520155,0.00003369183,0.00004868769,0.00007189874],"domain_scores_gemma":[0.999806,0.00003974374,0.00005501756,0.0000357079,0.00002245766,0.00004112357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008338396,0.00002094311,0.0004508975,0.00004093979,0.000006839351,0.0002772944,0.00005437003,0.00009330805,0.9939027,0.001463013,0.000193992,0.002661777],"study_design_scores_gemma":[0.00005888272,0.0002386309,0.01806679,0.00001254398,0.00001622767,0.001124782,0.000144679,0.001452601,0.9738165,0.001630786,0.003427886,0.000009654481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987513,0.004288153,0.004539465,0.0006531112,0.0001007194,0.00001889049,0.0001492673,0.0001475966,0.002589704],"genre_scores_gemma":[0.996427,0.0006674619,0.0008447521,0.00007160407,0.00003379184,0.00001586348,0.0001121834,0.00001270447,0.001814825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0012096,"threshold_uncertainty_score":0.005270243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003986411262510915,"score_gpt":0.2265952639315254,"score_spread":0.2226088526690145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}