{"id":"W1971186299","doi":"10.1242/dev.069344","title":"Transcriptional priming of intrathymic precursors for dendritic cell development","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"University of Toronto; Canadian Institutes of Health Research; Sunnybrook Research Institute","keywords":"Biology; Cell biology; Priming (agriculture); Dendritic cell; T cell; CCR4; C-C chemokine receptor type 7; Immunology; Chemokine; Immune system; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003190711,0.0001842094,0.0002464405,0.0001395882,0.0001952385,0.000004856213,0.0002248382,0.0001263167,0.0004440337],"category_scores_gemma":[0.00001919389,0.0001731473,0.000077865,0.0000733544,0.0001027046,0.00007039315,0.00002658101,0.0001081042,0.0001122313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006627321,"about_ca_system_score_gemma":0.0005546318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000723769,"about_ca_topic_score_gemma":0.000003547173,"domain_scores_codex":[0.9987876,0.00006770709,0.0005316273,0.0002209167,0.00004380264,0.000348307],"domain_scores_gemma":[0.9995515,0.0000814509,0.0001221151,0.0001383856,0.00009073143,0.00001585367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001041585,0.0004793171,0.0003560941,0.0001273455,0.0002982276,0.000001117175,0.02878755,5.91209e-7,0.9371107,0.0007028183,0.0005471818,0.03054751],"study_design_scores_gemma":[0.001239683,0.0001108711,0.01541041,0.00007085632,0.0000165421,0.00001245106,0.0004579887,2.208525e-7,0.8633794,0.00006086364,0.1190415,0.0001992382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842559,0.005532013,0.007589326,0.00001474066,0.0006606655,0.0004903763,0.00000796119,0.00004606608,0.001402992],"genre_scores_gemma":[0.9706098,0.00004959153,0.02486596,0.00008530102,0.000006129205,0.0001849712,0.00008923253,0.00002291081,0.004086119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1184943,"threshold_uncertainty_score":0.7060741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03682029943928359,"score_gpt":0.2248646471692378,"score_spread":0.1880443477299542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}