{"id":"W1971208013","doi":"10.1038/sj.gt.3301886","title":"Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Immunization; Genetic enhancement; Gene delivery; Virology; Medicine; Adenoviridae; Immunology; Biology; Antibody; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001692882,0.0004096297,0.0003145252,0.0002677344,0.0002680808,0.000401204,0.0003306438,0.0004505912,0.000582166],"category_scores_gemma":[0.0001613666,0.0002548268,0.0003545433,0.0001383341,0.0002871923,0.000518913,0.0003457878,0.0005589243,0.0003582998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002897832,"about_ca_system_score_gemma":0.0002384044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003034784,"about_ca_topic_score_gemma":0.0004983848,"domain_scores_codex":[0.9998653,0.00001453139,0.00001131734,0.00004048884,0.0000411929,0.00002715253],"domain_scores_gemma":[0.9998895,0.00002783554,0.00004185542,0.00001468191,0.00001184366,0.00001429255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001940776,0.00000836185,0.00004060447,0.00004242632,0.000002462989,0.00003802988,0.0000136634,0.00002950488,0.9950294,0.000211614,0.00005238202,0.004512074],"study_design_scores_gemma":[0.00000455896,0.00008396115,0.0003367682,0.000003321887,0.00001077334,0.0002285459,0.000006278005,0.000515222,0.9963515,0.0000435113,0.00240805,0.000007547464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6691625,0.0126386,0.3101367,0.0006176332,0.000374306,0.0002567447,0.0003501549,0.001211997,0.005251387],"genre_scores_gemma":[0.8862059,0.004611636,0.1044201,0.000191186,0.0001009819,0.0001990534,0.0001511988,0.000134118,0.003985842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000582166,"threshold_uncertainty_score":0.002102554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09270139581148576,"score_gpt":0.4009540400636902,"score_spread":0.3082526442522044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}