{"id":"W1971251879","doi":"10.1182/blood-2002-09-2725","title":"Synergy between all-trans retinoic acid and tumor necrosis factor pathways in acute leukemia cells","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Tumor necrosis factor alpha; Acute promyelocytic leukemia; Retinoic acid; Cancer research; Tretinoin; Biology; Leukemia; Molecular biology; Cell culture; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002254336,0.0003855156,0.0005677495,0.0003753645,0.0001765956,0.0004087805,0.0001983678,0.00027901,0.001861951],"category_scores_gemma":[0.0001540873,0.000228945,0.0004498589,0.0002725685,0.0001373753,0.0002423828,0.0003711071,0.0004577453,0.00107356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002362063,"about_ca_system_score_gemma":0.0003168979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002950004,"about_ca_topic_score_gemma":0.0005856619,"domain_scores_codex":[0.9996054,0.0001166628,0.00004545469,0.00006249556,0.0001010459,0.00006909577],"domain_scores_gemma":[0.9997675,0.00004855564,0.0000590466,0.00003942963,0.00002438792,0.00006106997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003034883,0.00003823991,0.0005062137,0.00007070168,0.00001385518,0.0001131045,0.00001501943,0.0001292591,0.9969701,0.00006928204,0.00005569087,0.00171496],"study_design_scores_gemma":[0.00009676225,0.001142612,0.00915222,0.0000179097,0.00005822827,0.0008886783,0.00008045969,0.001342918,0.9804153,0.0001940748,0.006602015,0.000008862014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761735,0.01168624,0.005843747,0.0002923061,0.00007476433,0.0001134045,0.0009204782,0.0002287167,0.004666957],"genre_scores_gemma":[0.9880189,0.002953455,0.004994169,0.0001865282,0.00003185641,0.00009228002,0.0008482681,0.00001740273,0.002857172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001861951,"threshold_uncertainty_score":0.006228864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01002806697089148,"score_gpt":0.2175672407298459,"score_spread":0.2075391737589544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}