{"id":"W1971273420","doi":"10.1111/j.1747-0285.2009.00803.x","title":"The Proteolytic Stability and Cytotoxicity Studies of <scp>l</scp>‐Aspartic Acid and <scp>l</scp>‐Diaminopropionic Acid derived β‐Peptides and a Mixed α/β‐Peptide","year":2009,"lang":"en","type":"letter","venue":"Chemical Biology & Drug Design","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aspartic acid; Peptide; Chemistry; Cytotoxicity; Biochemistry; Amino acid; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0008713561,0.0007993759,0.001324183,0.00006980747,0.0002828632,0.00007481457,0.0004900101,0.001281861,0.000002406614],"category_scores_gemma":[0.005551725,0.0005545666,0.0003010689,0.0001757168,0.002907376,0.00001188051,0.0005781133,0.000912544,0.000002798562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005470964,"about_ca_system_score_gemma":0.000107846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001310501,"about_ca_topic_score_gemma":0.000009917479,"domain_scores_codex":[0.9959373,0.0006062844,0.0008673136,0.001451883,0.0002250198,0.0009121776],"domain_scores_gemma":[0.9958976,0.002331141,0.0005313019,0.0007787446,0.0002414692,0.000219775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000249623,0.00006309945,0.0006713102,0.000247189,0.0006422997,0.000008181596,0.0001621987,1.917912e-7,0.9641885,0.000004281426,0.03268655,0.001301293],"study_design_scores_gemma":[0.0004989923,0.000231768,0.0002463626,0.0001011359,0.0004326577,0.00003065968,0.0003673313,0.0000222385,0.985565,0.001411155,0.01089275,0.0001999475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9595424,0.03245141,0.0001550899,0.006839266,0.00004528097,0.000814904,0.00006666297,0.00003324637,0.00005173177],"genre_scores_gemma":[0.982655,0.006998428,0.001168552,0.007766121,0.0005891891,0.0002684481,0.0001961478,0.0000623879,0.0002956878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02545298,"threshold_uncertainty_score":0.9998062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0232001564550812,"score_gpt":0.2455446978026701,"score_spread":0.2223445413475889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}