{"id":"W1971278448","doi":"10.1371/journal.pone.0052759","title":"Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Transcortin; Serpin; Cleavage (geology); Protein structure; Binding site; Chemistry; Plasma protein binding; Serine protease; Biology; Biochemistry; Protease; Biophysics; Globulin; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002366973,0.0002196529,0.0001838477,0.0001906971,0.0001540483,0.0003242043,0.000288297,0.0004320008,0.0008872067],"category_scores_gemma":[0.0002310002,0.00008140947,0.0002200524,0.0002034644,0.0003592,0.0002560816,0.0002180526,0.0003428617,0.0002661704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002338679,"about_ca_system_score_gemma":0.0001375061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000784829,"about_ca_topic_score_gemma":0.0006624448,"domain_scores_codex":[0.9999257,0.00001714692,0.000005182005,0.00002424606,0.00001505633,0.0000127725],"domain_scores_gemma":[0.9998541,0.00004100267,0.00003624247,0.00001897399,0.00002040771,0.0000293344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002481994,0.00001769587,0.004588184,0.000106029,0.00003927632,0.0003480551,0.0001006718,0.0002331235,0.9886506,0.0007604309,0.0001221962,0.004785632],"study_design_scores_gemma":[0.00005087831,0.0009500095,0.3597008,0.00008602833,0.0001950973,0.00693734,0.0005212394,0.003035414,0.5931963,0.00420025,0.03105377,0.00007279493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820936,0.01204842,0.00303063,0.0005716991,0.00004962012,0.00001055487,0.0003077578,0.00004176087,0.001845967],"genre_scores_gemma":[0.9956992,0.001877626,0.001110149,0.0002596605,0.00002031891,0.000004994249,0.0003906332,0.00001391619,0.0006235529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008872067,"threshold_uncertainty_score":0.002968013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1030452699976364,"score_gpt":0.2570987754954596,"score_spread":0.1540535054978233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}