{"id":"W1971280995","doi":"10.4161/auto.19768","title":"Caspase activation regulates the extracellular export of autophagic vacuoles","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Vacuole; Cell biology; Biology; Apoptosis; Lysosome; Intracellular; Caspase; Programmed cell death; Cytoplasm; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003418765,0.0001902206,0.0002967784,0.00008611804,0.0001103223,0.000009666798,0.00013972,0.0001175674,0.0009433335],"category_scores_gemma":[0.00006492226,0.0001262007,0.0001783261,0.0002288682,0.0001917318,0.0002181197,0.00003671704,0.000161882,0.00008298465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004355608,"about_ca_system_score_gemma":0.00009111739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002918709,"about_ca_topic_score_gemma":2.578589e-7,"domain_scores_codex":[0.9986952,0.00006562141,0.0003576927,0.0001836974,0.0003399158,0.000357901],"domain_scores_gemma":[0.9988506,0.0001113212,0.0001934209,0.0005960249,0.00008245995,0.000166179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005328146,0.00201274,0.01728353,0.0002856988,0.0007293823,0.0001185927,0.004438695,0.00002833543,0.8908269,0.03900415,0.004082019,0.04065717],"study_design_scores_gemma":[0.0008224986,0.0001062652,0.2171102,0.00005275902,0.0001408817,0.00007157356,0.0002009802,0.0001966701,0.7748244,0.000791161,0.005554134,0.0001284913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887794,0.00800813,0.0003195788,0.0004497452,0.0002406746,0.0003854823,0.000005079648,0.0001064685,0.001705443],"genre_scores_gemma":[0.9952937,0.00008739579,0.0003004691,0.0004401427,0.000391087,0.00003652444,0.00003357287,0.00003418314,0.003382863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1998267,"threshold_uncertainty_score":0.99997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02118460679519844,"score_gpt":0.2786958341620992,"score_spread":0.2575112273669007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}