{"id":"W1971293335","doi":"10.1242/jcs.002410","title":"Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones","year":2007,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Cytosol; Biology; Endoplasmic reticulum; Chaperone (clinical); Cell biology; Membrane protein; Hsp90; Biochemistry; Heat shock protein; Membrane; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001566119,0.00009394003,0.0001266597,0.0001665378,0.00007602207,0.00002283083,0.0003797863,0.00008233572,0.00004093721],"category_scores_gemma":[0.0003370909,0.00007569908,0.00008342574,0.0003666586,0.0003139143,0.0000249344,0.00004259914,0.0001422752,0.000003065278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002677163,"about_ca_system_score_gemma":0.0004623338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002200478,"about_ca_topic_score_gemma":0.000008866087,"domain_scores_codex":[0.9983438,0.00004243801,0.000413533,0.0001830738,0.0007549934,0.0002621724],"domain_scores_gemma":[0.9984705,0.00001613285,0.0001802002,0.0001649974,0.001016787,0.0001513996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001317604,0.00007612374,0.0001699147,0.00001135551,0.000006759857,0.000003742976,0.0001895139,0.00002125539,0.9959383,0.00002442157,0.0001027542,0.003324117],"study_design_scores_gemma":[0.0003642618,0.0007128186,0.001186639,0.00001480546,0.00000394842,0.00001681537,0.0001181045,0.00009940443,0.9954837,0.00005800012,0.001864243,0.00007726401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9457728,0.0004527428,0.0524018,0.0004971592,0.00003995995,0.0002025892,0.00001771554,0.000001717495,0.0006135255],"genre_scores_gemma":[0.991281,0.00003234916,0.008335242,0.00008179557,0.00002970747,0.000002002142,0.000008633756,0.000006347172,0.0002229477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04550818,"threshold_uncertainty_score":0.3086919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01044186295899059,"score_gpt":0.2846781690728974,"score_spread":0.2742363061139068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}