{"id":"W1971295897","doi":"10.1038/nature13346","title":"When lymphocytes run out of steam","year":2014,"lang":"en","type":"letter","venue":"Nature","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Immune system; Biology; Immunology; Immunodeficiency; Immunity; Phenotype; Gene; Severe combined immunodeficiency; Acquired immune system; Intrinsic immunity; Primary immunodeficiency; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001661156,0.0004705763,0.0005307983,0.0003141905,0.002561933,0.003294604,0.0008367016,0.01473742,0.005432016],"category_scores_gemma":[0.01237533,0.0003328523,0.0007431683,0.000172351,0.003361348,0.00302929,0.001553215,0.01907444,0.003506646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001723844,"about_ca_system_score_gemma":0.001084594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001715452,"about_ca_topic_score_gemma":0.002622405,"domain_scores_codex":[0.9987489,0.0004192068,0.00006394808,0.0001592561,0.0003407903,0.0002679605],"domain_scores_gemma":[0.9980717,0.001088975,0.0001445906,0.0001390955,0.0002085352,0.000347148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003485594,0.00004165348,0.001513839,0.00008939684,0.00005333651,0.006280824,0.0007767866,0.00008145469,0.001268413,0.02187754,0.9427596,0.02490859],"study_design_scores_gemma":[0.0001098636,0.00007380726,0.0007616297,0.0001505699,0.00004083046,0.003832946,0.001462213,0.0001772374,0.001497933,0.04427102,0.9475803,0.00004178358],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002802884,0.004771009,0.0007081698,0.9295142,0.05006604,0.00001288839,0.00004190063,0.00009610213,0.01198689],"genre_scores_gemma":[0.05547278,0.003610368,0.0005813276,0.8534409,0.04347812,0.00004435326,0.00004711574,0.0000964818,0.04322856],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01473742,"threshold_uncertainty_score":0.01817191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009140439785913598,"score_gpt":0.2684828683109912,"score_spread":0.2593424285250776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}