{"id":"W1971375423","doi":"10.1002/stem.12","title":"Early Beneficial Effects of Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Akt on Cardiac Metabolism After Myocardial Infarction","year":2009,"lang":"en","type":"article","venue":"Stem Cells","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondazione Cariplo; National Institutes of Health; Ministero dell’Istruzione, dell’Università e della Ricerca; Fondazione IRCCS Policlinico San Matteo; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Mesenchymal stem cell; Protein kinase B; Biology; Stem cell; PI3K/AKT/mTOR pathway; Myocardial infarction; Pharmacology; Internal medicine; Endocrinology; Cancer research; Apoptosis; Medicine; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007704931,0.0006002008,0.001524007,0.0005018747,0.0001566454,0.000100443,0.0002312993,0.0004650423,0.0001523236],"category_scores_gemma":[0.0000263665,0.0005353644,0.0007254076,0.0005588954,0.0001491272,0.0002453402,0.0001361269,0.0007370251,0.0002931049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002263205,"about_ca_system_score_gemma":0.000214369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001413395,"about_ca_topic_score_gemma":0.000001656818,"domain_scores_codex":[0.9946019,0.000565715,0.0009101915,0.0008961404,0.001964702,0.001061333],"domain_scores_gemma":[0.9973598,0.0004312663,0.0003378874,0.000987638,0.0003210217,0.0005624423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001948658,0.0002896952,0.0007732958,0.0005740408,0.0002337052,0.0002033944,0.0008022744,0.0000597281,0.9746417,0.00008613166,0.0006824502,0.01970491],"study_design_scores_gemma":[0.002501394,0.001355091,0.0544796,0.0006509629,0.0003546847,0.000009483984,0.0001208874,0.00006366,0.9365532,0.00003550211,0.003415222,0.0004603658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864237,0.002334392,0.00005860801,0.0001484621,0.001833474,0.001981125,0.00005157163,0.0001141943,0.007054524],"genre_scores_gemma":[0.9956258,0.0001789869,0.0002725406,0.0002332268,0.0009919739,0.00006868845,0.000009989077,0.00008913637,0.002529643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0537063,"threshold_uncertainty_score":0.9997098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01133128920673325,"score_gpt":0.2479847837833641,"score_spread":0.2366534945766308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}