{"id":"W1971375423","doi":"10.1002/stem.12","title":"Early Beneficial Effects of Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Akt on Cardiac Metabolism After Myocardial Infarction","year":2009,"lang":"en","type":"article","venue":"Stem Cells","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondazione Cariplo; National Institutes of Health; Ministero dell’Istruzione, dell’Università e della Ricerca; Fondazione IRCCS Policlinico San Matteo; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Mesenchymal stem cell; Protein kinase B; Biology; Stem cell; PI3K/AKT/mTOR pathway; Myocardial infarction; Pharmacology; Internal medicine; Endocrinology; Cancer research; Apoptosis; Medicine; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001906699,0.0005750023,0.0005241992,0.000287808,0.0001138165,0.0002345805,0.0001481115,0.0002433618,0.0008624106],"category_scores_gemma":[0.0001103898,0.0001522204,0.0003116784,0.0001674802,0.0003181229,0.0002475114,0.0001939655,0.0006059321,0.0001557089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008450758,"about_ca_system_score_gemma":0.0002256901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001854657,"about_ca_topic_score_gemma":0.0003676633,"domain_scores_codex":[0.9999117,0.00001550658,0.00001028145,0.00001201861,0.00001936912,0.00003120625],"domain_scores_gemma":[0.9999193,0.00001152325,0.00002402852,0.000007089876,0.000007459925,0.00003055421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003441475,0.0004793763,0.0005503829,0.0001607984,0.00001799774,0.0001191628,0.00002938046,0.0001032653,0.9866393,0.0001010337,0.00006123658,0.008296593],"study_design_scores_gemma":[0.000639152,0.01493613,0.03411572,0.00005209381,0.0001987809,0.0002869067,0.0001089413,0.0009961553,0.9466117,0.0002172064,0.001816605,0.00002053377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955336,0.002943584,0.000655974,0.00008048738,0.00005441916,0.00003398768,0.0001039354,0.00004683469,0.000547107],"genre_scores_gemma":[0.994703,0.003155943,0.0009828835,0.00007292685,0.00004407859,0.00005102932,0.0002578983,0.000009266163,0.0007229233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008624106,"threshold_uncertainty_score":0.002885103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01133128920673325,"score_gpt":0.2479847837833641,"score_spread":0.2366534945766308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}