{"id":"W1971375786","doi":"10.1038/oby.2001.43","title":"The Trp64Arg Polymorphism of the β3‐Adrenergic Receptor Gene Is Not Associated with Training‐Induced Changes in Body Composition: The HERITAGE Family Study","year":2001,"lang":"en","type":"article","venue":"Obesity Research","topic":"Genetics and Physical Performance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Heart, Lung, and Blood Institute","keywords":"Endocrinology; Lean body mass; Internal medicine; Polymorphism (computer science); Medicine; Adrenergic receptor; Body mass index; Allele; Genotype; Beta-3 adrenergic receptor; Gene polymorphism; Endurance training; Body fat percentage; Receptor; Gene; Biology; Genetics; Body weight","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004670483,0.0006297147,0.0003769551,0.0003553737,0.0005104535,0.0002547496,0.000234702,0.00036247,0.003493954],"category_scores_gemma":[0.001266573,0.0002090435,0.0003361537,0.0002717926,0.0004094408,0.000182978,0.0002572362,0.0004459803,0.0002355839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001162252,"about_ca_system_score_gemma":0.000210517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003525162,"about_ca_topic_score_gemma":0.002841674,"domain_scores_codex":[0.9996855,0.0001003112,0.00001873326,0.00008210328,0.00006616583,0.00004727162],"domain_scores_gemma":[0.9994306,0.0001462161,0.0001451451,0.00007293087,0.00004038491,0.0001647411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003945305,0.0006474548,0.9360507,0.00005522987,0.000626991,0.007722119,0.0008718669,0.000232507,0.03786984,0.0002779667,0.0005753692,0.01112476],"study_design_scores_gemma":[0.0001981558,0.00137374,0.9836085,0.00002587577,0.0002843772,0.01059283,0.0002532888,0.0004773854,0.002103288,0.0001518715,0.0009113241,0.00001934709],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993442,0.00009129709,0.0002081112,0.00003578565,0.000006636297,0.000004640098,0.00008447306,0.000003488568,0.0002213807],"genre_scores_gemma":[0.9992853,0.00007378089,0.0001366167,0.00002960901,0.00001545262,0.000005053196,0.00008108618,0.000004938408,0.0003681121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003525162,"threshold_uncertainty_score":0.01168847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06667174540377874,"score_gpt":0.313585943175946,"score_spread":0.2469141977721672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}