{"id":"W1971375786","doi":"10.1038/oby.2001.43","title":"The Trp64Arg Polymorphism of the β3‐Adrenergic Receptor Gene Is Not Associated with Training‐Induced Changes in Body Composition: The HERITAGE Family Study","year":2001,"lang":"en","type":"article","venue":"Obesity Research","topic":"Genetics and Physical Performance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Heart, Lung, and Blood Institute","keywords":"Endocrinology; Lean body mass; Internal medicine; Polymorphism (computer science); Medicine; Adrenergic receptor; Body mass index; Allele; Genotype; Beta-3 adrenergic receptor; Gene polymorphism; Endurance training; Body fat percentage; Receptor; Gene; Biology; Genetics; Body weight","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001081859,0.0001294024,0.0001514671,0.00002769131,0.0005170286,0.00004898441,0.00064719,0.0000903101,0.00001299926],"category_scores_gemma":[0.00004097302,0.00006696647,0.00005692229,0.0004489482,0.0002669278,0.000002991797,0.0002436793,0.0003325379,0.000004145224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002617907,"about_ca_system_score_gemma":0.0001083761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001889236,"about_ca_topic_score_gemma":0.001010539,"domain_scores_codex":[0.9981123,0.000492811,0.0001624264,0.0002723598,0.0005558977,0.000404176],"domain_scores_gemma":[0.9990206,0.00008500876,0.0000707815,0.0005742938,0.0001957824,0.00005357417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002208474,0.0005135355,0.01986224,0.000004138576,0.00007640827,0.000003501473,0.0009654381,0.00002204554,0.9771636,0.00002623347,0.0003723193,0.0007697291],"study_design_scores_gemma":[0.001080197,0.001632602,0.5138646,0.0000331556,0.00001480335,0.000003803805,0.001644855,0.0002491515,0.4796509,0.00004477593,0.001609337,0.0001718084],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968261,0.0002435091,0.000001328111,0.001704325,0.00005508757,0.0004880361,0.00002241836,0.00000336187,0.0006558013],"genre_scores_gemma":[0.9983327,0.0002387435,0.000005699018,0.0001716048,0.0001419331,0.00005676092,0.00001733768,0.00001627414,0.001018941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4975126,"threshold_uncertainty_score":0.3976618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06667174540377874,"score_gpt":0.313585943175946,"score_spread":0.2469141977721672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}