{"id":"W1971381741","doi":"10.1016/j.ejca.2008.10.021","title":"Do BRCA1 modifiers also affect the risk of breast cancer in non-carriers?","year":2008,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Coalition for Research in Women's Health","funders":"","keywords":"Breast cancer; Odds ratio; Single-nucleotide polymorphism; Genotype; Internal medicine; Oncology; Medicine; Confidence interval; Case-control study; Cancer; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005827759,0.0005393521,0.0007046941,0.0009823813,0.000431526,0.0005238066,0.0005309833,0.001260067,0.005325101],"category_scores_gemma":[0.003427157,0.0002752991,0.0005630637,0.0007597943,0.0004379932,0.0006778393,0.0002386482,0.0005804186,0.0005495331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000144182,"about_ca_system_score_gemma":0.0001753353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00242138,"about_ca_topic_score_gemma":0.001521464,"domain_scores_codex":[0.9997173,0.00009239728,0.00002144041,0.00005422217,0.00004857598,0.00006593663],"domain_scores_gemma":[0.9986261,0.00068833,0.0003608086,0.0001137688,0.00006880055,0.0001421291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003102558,0.0002798571,0.9540458,0.00009346741,0.0004094475,0.003998461,0.000423627,0.0001467305,0.01551176,0.0005538952,0.0007411636,0.0206931],"study_design_scores_gemma":[0.00004439003,0.0003147222,0.9917692,0.000014167,0.0003742915,0.004392439,0.000180547,0.0002025114,0.001189138,0.0005797594,0.0009248258,0.00001405638],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948484,0.002221664,0.0001778112,0.0005330801,0.00005157317,0.000006454573,0.0002484189,0.00001901889,0.001893604],"genre_scores_gemma":[0.9981298,0.0006982287,0.0001176574,0.0001090147,0.00005921617,0.000003697462,0.000103429,0.000009577352,0.0007693234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005325101,"threshold_uncertainty_score":0.01781428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01141086556452997,"score_gpt":0.2720901008933277,"score_spread":0.2606792353287978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}