{"id":"W1971403469","doi":"10.1016/j.carpath.2004.03.140","title":"INCREASED MMP-2 PRODUCTION IN RESPONSE TO ACTIN CYTOSKELETON DEPOLYMERIZATION IS RAC/CDC42 DEPENDENT IN SKELETAL MUSCLE ENDOTHELIAL CELLS","year":2004,"lang":"en","type":"article","venue":"Cardiovascular Pathology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"","keywords":"CDC42; Cell biology; Depolymerization; Cytoskeleton; Actin; Actin cytoskeleton; Chemistry; Skeletal muscle; RAC1; Biology; Anatomy; Biochemistry; Signal transduction; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002605543,0.0003395884,0.0005189941,0.0004535148,0.0004467889,0.0005223737,0.0002520947,0.0004209948,0.002501751],"category_scores_gemma":[0.000203899,0.0004113468,0.0005438129,0.0003741154,0.0002829271,0.0003585595,0.0003052671,0.001120797,0.0007321774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004260267,"about_ca_system_score_gemma":0.0002883399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002109564,"about_ca_topic_score_gemma":0.003013589,"domain_scores_codex":[0.9996152,0.00005613346,0.00003836023,0.00005903086,0.00008997294,0.0001413274],"domain_scores_gemma":[0.999738,0.00003964263,0.00003097935,0.0000574375,0.00004610688,0.00008777253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002243574,0.00004322006,0.0002089371,0.00002061124,0.0000046351,0.00009133096,0.00001766378,0.00001502132,0.9988706,0.00003460656,0.00005097354,0.0004180669],"study_design_scores_gemma":[0.00004358097,0.000283049,0.03508201,0.000005589286,0.000018209,0.000313897,0.00008844471,0.001017325,0.961829,0.00004405144,0.001266426,0.000008353386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945337,0.001279209,0.001797915,0.0002074459,0.00007240168,0.00002972204,0.0007137474,0.00009006592,0.001275852],"genre_scores_gemma":[0.9916169,0.0007211988,0.001621624,0.00008455305,0.0000528661,0.00009304332,0.001146935,0.00002222947,0.004640645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002501751,"threshold_uncertainty_score":0.008369207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006679314176987707,"score_gpt":0.2229231181654127,"score_spread":0.216243803988425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}