{"id":"W1971403469","doi":"10.1016/j.carpath.2004.03.140","title":"INCREASED MMP-2 PRODUCTION IN RESPONSE TO ACTIN CYTOSKELETON DEPOLYMERIZATION IS RAC/CDC42 DEPENDENT IN SKELETAL MUSCLE ENDOTHELIAL CELLS","year":2004,"lang":"en","type":"article","venue":"Cardiovascular Pathology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"","keywords":"CDC42; Cell biology; Depolymerization; Cytoskeleton; Actin; Actin cytoskeleton; Chemistry; Skeletal muscle; RAC1; Biology; Anatomy; Biochemistry; Signal transduction; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007889959,0.0002251172,0.0003234627,0.0002917577,0.00006404072,0.00002095307,0.0001738642,0.000269549,0.00001615879],"category_scores_gemma":[0.0003386899,0.0002572464,0.0003494099,0.0003045621,0.00003518194,0.00001424522,0.0001210923,0.0002150177,0.00004018474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001061288,"about_ca_system_score_gemma":0.0001445481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002885913,"about_ca_topic_score_gemma":0.000195382,"domain_scores_codex":[0.997797,0.0004871288,0.0003541371,0.0007647954,0.0002125314,0.0003843743],"domain_scores_gemma":[0.9990306,0.00001265644,0.00006886227,0.0007320617,0.00005479385,0.000101023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002472643,0.0001438546,0.00008655446,0.00001020653,0.00006045045,0.0001708703,0.0002154467,0.003300464,0.9905608,0.00000942626,0.0000157533,0.005178931],"study_design_scores_gemma":[0.001576658,0.0002766942,0.002692733,0.00002069958,0.00003539375,0.0002276878,0.0001347462,0.00001711351,0.9849821,0.00003322,0.009728981,0.0002739766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860603,0.0007016509,0.01156473,0.0002558732,0.0006975639,0.0005481532,0.00003158866,0.00001795067,0.0001222177],"genre_scores_gemma":[0.9982724,0.000263061,0.0005706451,0.0002752451,0.0002672287,0.0001278503,0.0001010568,0.00004453426,0.00007793244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01221217,"threshold_uncertainty_score":0.999988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006679314176987707,"score_gpt":0.2229231181654127,"score_spread":0.216243803988425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}