{"id":"W1971465234","doi":"10.1016/j.chembiol.2010.05.010","title":"Chemical Genomic Approaches to Study Model Microbes","year":2010,"lang":"en","type":"review","venue":"Chemistry & Biology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Computational biology; Biology; Genome; Gene regulatory network; Biological network; Systems biology; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000214589,0.0006005617,0.002122233,0.00005786744,0.00005397626,0.000017754,0.0004937017,0.001210624,0.0002300217],"category_scores_gemma":[0.0001889729,0.0004021063,0.0004477081,0.0001712976,0.0001485156,0.000009846795,0.0003575213,0.001167156,0.0001371672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001041892,"about_ca_system_score_gemma":0.0002726401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004251131,"about_ca_topic_score_gemma":4.571707e-7,"domain_scores_codex":[0.9977455,0.00003587111,0.0005984509,0.001101289,0.00006667775,0.0004522792],"domain_scores_gemma":[0.9985947,0.00005039146,0.0001898385,0.0008767555,0.00004723975,0.0002410899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002257991,0.0003023251,0.000002402538,0.003794777,0.0001853753,0.000008565564,0.00002530192,3.721652e-8,0.5313812,0.000002345637,0.0005829613,0.4636921],"study_design_scores_gemma":[0.0002336268,0.00004869626,3.884755e-7,0.0006715293,0.0012058,0.0003037065,0.00001206298,0.000003066076,0.07731061,0.00001079965,0.9197133,0.0004864195],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02812222,0.9693102,0.000003750766,0.0002630838,0.0001243211,0.001360764,0.0001255861,0.00007456877,0.0006155199],"genre_scores_gemma":[0.006142167,0.9864776,0.002326886,0.0001745304,0.001634643,0.00004275523,0.0007100059,0.0001060612,0.002385426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9191303,"threshold_uncertainty_score":0.9998431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1423010007670619,"score_gpt":0.3210113161140626,"score_spread":0.1787103153470007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}