{"id":"W1971465234","doi":"10.1016/j.chembiol.2010.05.010","title":"Chemical Genomic Approaches to Study Model Microbes","year":2010,"lang":"en","type":"review","venue":"Chemistry & Biology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Computational biology; Biology; Genome; Gene regulatory network; Biological network; Systems biology; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008720501,0.001760258,0.001535473,0.001815556,0.0003489887,0.001055351,0.001399718,0.001220556,0.002643691],"category_scores_gemma":[0.0006786453,0.0004625509,0.000591159,0.001862842,0.001427901,0.001661331,0.0011238,0.00253611,0.002515211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001646012,"about_ca_system_score_gemma":0.001453546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001450079,"about_ca_topic_score_gemma":0.002706745,"domain_scores_codex":[0.9998006,0.00002810986,0.00001423126,0.00003696395,0.00009933471,0.00002080232],"domain_scores_gemma":[0.9996903,0.000144359,0.00002199129,0.00002440006,0.00008249571,0.00003650253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001202432,0.0001588749,0.0001405812,0.007978472,0.00007768388,0.0002153,0.00004410022,0.001414742,0.02750611,0.02466757,0.03697082,0.9007056],"study_design_scores_gemma":[0.00003796819,0.00005470419,0.0002156461,0.0005040744,0.0000626207,0.0003812921,0.00002507166,0.0002361989,0.006145936,0.006214091,0.9860983,0.00002424656],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003819375,0.9866015,0.005963428,0.0007567707,0.001083275,0.00002933834,0.00006899151,0.00005578201,0.005058953],"genre_scores_gemma":[0.001493722,0.9912069,0.003716948,0.0005633485,0.0004198489,0.00003940305,0.0001017272,0.000007351955,0.002450743],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002643691,"threshold_uncertainty_score":0.01194268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1423010007670619,"score_gpt":0.3210113161140626,"score_spread":0.1787103153470007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}