{"id":"W1971474467","doi":"10.1074/jbc.m600296200","title":"Aggrecan Turnover in Human Intervertebral Disc as Determined by the Racemization of Aspartic Acid","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Healthcare and Venom Research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"European Commission; University of Oxford","keywords":"Racemization; Aggrecan; Intervertebral disc; Aspartic acid; Chemistry; Biochemistry; Medicine; Amino acid; Stereochemistry; Anatomy; Osteoarthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003840511,0.0002076216,0.0001974588,0.0003904953,0.000137491,0.0003947654,0.0001355716,0.0002599943,0.0007284377],"category_scores_gemma":[0.0005764331,0.0001317484,0.0001654159,0.0002005944,0.0002046596,0.0002145203,0.0001147981,0.0002201756,0.0004147716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001877444,"about_ca_system_score_gemma":0.0001010403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049143,"about_ca_topic_score_gemma":0.0006062135,"domain_scores_codex":[0.9998465,0.00003723948,0.00001771008,0.00004414998,0.00003209851,0.00002231048],"domain_scores_gemma":[0.999699,0.00005857465,0.0001020042,0.00003769132,0.00006262128,0.00004016293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008108905,0.00002659979,0.01119357,0.00002946118,0.0000154854,0.00009675798,0.0001736747,0.0000551426,0.9834078,0.00005436629,0.00002431733,0.00411193],"study_design_scores_gemma":[0.00005016962,0.001593697,0.2442547,0.00001791274,0.00007244688,0.00203274,0.0002377901,0.001912085,0.7465152,0.0001598178,0.003125043,0.00002845841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970167,0.001631363,0.0008716133,0.00002030316,0.000003976952,0.00000929392,0.0001359891,0.0000120267,0.0002987858],"genre_scores_gemma":[0.9961969,0.0007443908,0.00129403,0.00002827846,0.000006112823,0.0000246339,0.0004076938,0.000008064934,0.00128987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001049143,"threshold_uncertainty_score":0.002436817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0426324180372171,"score_gpt":0.3591743080525933,"score_spread":0.3165418900153761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}