{"id":"W1971489011","doi":"10.1128/aac.01802-13","title":"Antimicrobial Activity of Ceftolozane-Tazobactam Tested against Enterobacteriaceae and Pseudomonas aeruginosa with Various Resistance Patterns Isolated in U.S. Hospitals (2011-2012)","year":2013,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":202,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Astellas Pharma","keywords":"Pseudomonas aeruginosa; Broth microdilution; Microbiology; Enterobacteriaceae; Antimicrobial; Minimum inhibitory concentration; Tazobactam; Biology; Multiple drug resistance; Antibiotics; Drug resistance; Escherichia coli; Antibiotic resistance; Bacteria; Imipenem; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002595492,0.0003501623,0.0002789603,0.0005674593,0.000118741,0.0002194013,0.0001552889,0.0002829536,0.0005445314],"category_scores_gemma":[0.0008887495,0.0001701044,0.0002553222,0.0005458932,0.0001399968,0.0002171789,0.0001627134,0.0002347805,0.0001133562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002578505,"about_ca_system_score_gemma":0.0003060543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004103872,"about_ca_topic_score_gemma":0.01124247,"domain_scores_codex":[0.999699,0.00006119347,0.00006346902,0.00005603407,0.00008540681,0.00003487307],"domain_scores_gemma":[0.9996213,0.00007628396,0.0001272139,0.00001322431,0.00009611117,0.00006580003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008090063,0.001235022,0.369884,0.0006687446,0.0003690018,0.0009126479,0.0005747244,0.0007893088,0.5483045,0.00004390365,0.0004685017,0.06865962],"study_design_scores_gemma":[0.0004276737,0.01739132,0.8611835,0.00008811837,0.0003198133,0.002792782,0.0004938839,0.001176646,0.1131223,0.00002005364,0.002951976,0.00003190979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984058,0.001172849,0.00004350307,0.00002213262,0.000004921233,0.00001134004,0.0001658225,0.000003991192,0.000169759],"genre_scores_gemma":[0.9981717,0.0007804435,0.0003351823,0.00003577063,0.000006705878,0.000008053825,0.000508715,0.000001485128,0.0001519438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004103872,"threshold_uncertainty_score":0.008159935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003893837712500148,"score_gpt":0.2046078700618255,"score_spread":0.2007140323493253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}