{"id":"W1971491328","doi":"10.1371/journal.pgen.1003479","title":"A Compendium of Nucleosome and Transcript Profiles Reveals Determinants of Chromatin Architecture and Transcription","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Occupational Cancer Research Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Nucleosome; Biology; Genetics; Chromatin; Histone; Histone methylation; SWI/SNF; Transcription (linguistics); Histone code; Cell biology; Gene; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002341454,0.0002217986,0.0002952103,0.0006523096,0.0001578373,0.0003392647,0.0001524502,0.0001331592,0.0005230328],"category_scores_gemma":[0.000533194,0.0001897994,0.0002244335,0.0004751232,0.000144381,0.0001361444,0.0002009727,0.0002849458,0.0002230545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306549,"about_ca_system_score_gemma":0.0001515379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001016432,"about_ca_topic_score_gemma":0.002194724,"domain_scores_codex":[0.999828,0.00001493913,0.00001358715,0.00006209037,0.00006414392,0.00001721839],"domain_scores_gemma":[0.9996079,0.0001106168,0.00008720454,0.00006392488,0.00008495559,0.00004539381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007830903,0.000009394265,0.00753073,0.00003779864,0.00002492702,0.0000323744,0.00005667439,0.0002232698,0.9842709,0.00006325628,0.00007003942,0.007602377],"study_design_scores_gemma":[0.00001299282,0.0004591317,0.6607555,0.00002200778,0.0001461171,0.001212301,0.0001120936,0.00553478,0.3244707,0.0002474636,0.006982066,0.00004484794],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778275,0.0008004625,0.01409423,0.0000418485,0.0000113961,0.00003218535,0.005849982,0.0001828094,0.001159603],"genre_scores_gemma":[0.9404381,0.0009619812,0.03169336,0.00008700176,0.00002014059,0.0001140419,0.02391602,0.0001530741,0.002616262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001016432,"threshold_uncertainty_score":0.002021015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007579710999937687,"score_gpt":0.2031002948463543,"score_spread":0.1955205838464166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}