{"id":"W1971521918","doi":"10.1103/physrevlett.90.258104","title":"Origins of Chevron Rollovers in Non-Two-State Protein Folding Kinetics","year":2003,"lang":"en","type":"article","venue":"Physical Review Letters","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Natural Sciences and Engineering Research Council of Canada","funders":"","keywords":"Chevron (anatomy); Protein folding; Folding (DSP implementation); Kinetics; Native state; Logarithm; Chemical physics; Physics; Lattice (music); Kinetic energy; Trapping; Statistical physics; Crystallography; Chemistry; Geology; Classical mechanics; Biology; Mathematics; Nuclear magnetic resonance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001147139,0.0001527848,0.0002774909,0.0000219655,0.00001186307,0.000005177459,0.0001342893,0.00001649837,0.000003504438],"category_scores_gemma":[0.00007769921,0.0001349956,0.0001286687,0.0001493596,0.00005193844,0.000004054618,0.00003466544,0.0001039408,0.00000406622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004975506,"about_ca_system_score_gemma":0.00002246373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002290388,"about_ca_topic_score_gemma":0.000008138793,"domain_scores_codex":[0.9991323,0.00006375463,0.0002181475,0.0002403679,0.0001268607,0.0002185502],"domain_scores_gemma":[0.9995366,0.000008216861,0.0001067504,0.0002757054,0.00002303693,0.00004963914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009838735,0.0000419363,0.0001714655,0.0003209432,0.00001550479,0.000002997203,0.00001219231,0.0003343179,0.9972372,0.0006580963,0.00006802283,0.001127459],"study_design_scores_gemma":[0.001007594,0.0002501617,0.0005185965,0.000898222,0.00004751301,0.000005089073,0.000004221532,0.0003557767,0.9670534,0.0006005282,0.02883958,0.0004193806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955208,0.001945025,0.001438409,0.000230913,0.00003653195,0.0004902419,0.000006089442,0.00000390147,0.0003281283],"genre_scores_gemma":[0.9961321,0.0008189667,0.001006385,0.001911016,0.00005267751,0.00003654633,0.00001523707,0.00001726952,0.000009748076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03018389,"threshold_uncertainty_score":0.5504959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005690234353472812,"score_gpt":0.2652734299833224,"score_spread":0.2595831956298496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}