{"id":"W1971582979","doi":"10.1242/dev.038828","title":"Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2","year":2010,"lang":"en","type":"article","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":481,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Discovery Centre","funders":"Canadian Institutes of Health Research; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences","keywords":"Trophoblast; Biology; Blastocyst; Embryonic stem cell; Inner cell mass; GATA3; Transcription factor; Stem cell; Cell biology; CDX2; RUNX2; Embryo; Genetics; Placenta; Embryogenesis; Gene; Homeobox; Fetus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001211498,0.0002257971,0.0001408133,0.0002159781,0.0002055089,0.000303418,0.0001539358,0.0001851627,0.001500988],"category_scores_gemma":[0.000142263,0.0001712328,0.0002110623,0.0001438086,0.0003115424,0.0001710908,0.0002791617,0.0003433425,0.0004604634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004435363,"about_ca_system_score_gemma":0.0003402196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001037046,"about_ca_topic_score_gemma":0.001773685,"domain_scores_codex":[0.999868,0.00002390209,0.000008250483,0.00004317893,0.00003120784,0.00002543515],"domain_scores_gemma":[0.9998945,0.00001622143,0.00003360434,0.00001230629,0.00001396578,0.00002945246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005238076,0.000002991723,0.0004211928,0.00001116766,0.000001876634,0.00004254479,0.00001321351,0.00003972086,0.9986016,0.0001926011,0.00001838578,0.0006022225],"study_design_scores_gemma":[0.00002787594,0.0000577592,0.02828047,0.000006284041,0.00001229831,0.0003372871,0.00004083412,0.001198983,0.9655603,0.0002143151,0.0042585,0.000005213286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830037,0.001592938,0.008615297,0.000229414,0.00003920409,0.00002673943,0.0004105619,0.0002129929,0.005868988],"genre_scores_gemma":[0.9873936,0.0005189647,0.003874863,0.0001088879,0.000008493857,0.00002815153,0.0003533064,0.00005746658,0.007656299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001500988,"threshold_uncertainty_score":0.005021334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005914087330131185,"score_gpt":0.2278888029162622,"score_spread":0.221974715586131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}