{"id":"W1971588030","doi":"10.1074/jbc.m504913200","title":"A Novel Mechanism for the Suppression of a Voltage-gated Potassium Channel by Glucose-dependent Insulinotropic Polypeptide","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Potassium channel; Mechanism (biology); Voltage-gated potassium channel; Biophysics; Chemistry; Potassium; Channel (broadcasting); Voltage-gated ion channel; Internal medicine; Endocrinology; Biochemistry; Ion channel; Biology; Computer science; Medicine; Physics; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392883,0.0001411853,0.0001945887,0.00001588931,0.00007194161,0.00001198005,0.0002319515,0.0002907142,0.00004814017],"category_scores_gemma":[0.0002612277,0.00008274489,0.000204022,0.00005244534,0.00006981324,0.00000591459,0.00006228977,0.0001526515,9.427786e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002418606,"about_ca_system_score_gemma":0.00004317666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002449291,"about_ca_topic_score_gemma":4.488825e-7,"domain_scores_codex":[0.9990402,0.00001844726,0.0004355905,0.0001676618,0.0001640862,0.0001739478],"domain_scores_gemma":[0.9989867,0.00004346659,0.0004304143,0.0001513923,0.0003048276,0.00008316716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004624149,0.0001690854,0.00002816073,0.00001549307,0.0000572001,4.455477e-7,0.00001287752,0.000169326,0.9952669,0.00001895028,0.002584912,0.001214276],"study_design_scores_gemma":[0.001275713,0.0003387877,0.0001270791,0.00001751236,0.00002449601,0.00007045617,0.0001019136,0.001063839,0.9840336,0.00008787047,0.01275547,0.0001032452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8665769,0.001026502,0.1305002,0.001183797,0.0003516545,0.0001712152,0.00009334276,0.000008508541,0.00008787338],"genre_scores_gemma":[0.9971693,0.00030936,0.0006449182,0.0002760567,0.0009922434,0.000006969623,0.00006617737,0.00001100673,0.0005239732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1305924,"threshold_uncertainty_score":0.3374239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01876342353446156,"score_gpt":0.2465733257757361,"score_spread":0.2278099022412745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}