{"id":"W1971651401","doi":"10.1073/pnas.1405154111","title":"Two-photon imaging of Zn <sup>2+</sup> dynamics in mossy fiber boutons of adult hippocampal slices","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Trace Elements in Health","field":"Nursing","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; RIKEN Brain Science Institute; Canadian Institutes of Health Research; National Institutes of Health; RIKEN; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Massachusetts Institute of Technology","keywords":"Glutamatergic; Mossy fiber (hippocampus); Synaptic vesicle; Zinc; Hippocampal formation; Vesicle; Neuroscience; Biophysics; Chemistry; Fluorescence; Biology; Biochemistry; Glutamate receptor; Physics; Optics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002325616,0.0001340644,0.0002966239,0.0003676029,0.0001316318,0.00001766811,0.0009982141,0.00007691728,0.00001912324],"category_scores_gemma":[0.001184115,0.0001046527,0.00008260127,0.0009809606,0.001047899,0.0005906711,0.0001298838,0.0002729348,9.236491e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001561648,"about_ca_system_score_gemma":0.00004584912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00018964,"about_ca_topic_score_gemma":0.000003721895,"domain_scores_codex":[0.9971084,0.00002385187,0.0007892692,0.0002999757,0.001490856,0.0002876642],"domain_scores_gemma":[0.998095,0.0003633694,0.001005608,0.00002072903,0.000471786,0.00004348968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001950661,0.0003761247,0.7875884,0.001132647,0.00002946944,8.865953e-9,0.00396151,0.004794651,0.0611722,0.1303468,0.0005175893,0.00988557],"study_design_scores_gemma":[0.001504177,0.0002506502,0.1712641,0.001324896,0.00004917927,0.00001002278,0.004914901,0.3125712,0.4017653,0.1058563,0.0001632241,0.0003260622],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890435,0.00004901877,0.000001035776,0.004294339,0.00004534865,0.0002686396,0.00003402806,0.00001222002,0.00625188],"genre_scores_gemma":[0.9935127,0.000007367108,0.0061287,0.0002367168,0.00005748576,0.00000861564,3.967056e-7,0.000008613835,0.00003942195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6163242,"threshold_uncertainty_score":0.4267614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02049500341600811,"score_gpt":0.323775158974326,"score_spread":0.3032801555583179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}