{"id":"W1971664780","doi":"10.1371/journal.ppat.1004606","title":"mir-233 Modulates the Unfolded Protein Response in C. elegans during Pseudomonas aeruginosa Infection","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Education of the People's Republic of China; National Natural Science Foundation of China; University of Texas Health Science Center at Houston; National Key Research and Development Program of China; McMaster University","keywords":"Unfolded protein response; Pseudomonas aeruginosa; Innate immune system; Endoplasmic reticulum; Gene knockdown; Caenorhabditis elegans; Biology; Cell biology; microRNA; RNA interference; Mutant; Immune system; RNA; Genetics; Gene; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001139459,0.0003795363,0.0002493918,0.0003174546,0.0002832704,0.0002718878,0.0002199605,0.0003680398,0.0006287292],"category_scores_gemma":[0.0001399225,0.0001914061,0.0002557171,0.00008626159,0.0002913678,0.0002022121,0.0003085207,0.0005660926,0.0002571579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004400882,"about_ca_system_score_gemma":0.0002993294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001107032,"about_ca_topic_score_gemma":0.00192748,"domain_scores_codex":[0.9998939,0.00001168708,0.00001008649,0.00002929062,0.00002943236,0.00002551506],"domain_scores_gemma":[0.9998422,0.00001626963,0.00005838008,0.000009877981,0.00002221349,0.00005110878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000656773,0.00001247939,0.0001240586,0.00001728286,0.000002008554,0.00004707669,0.00001120171,0.00003838182,0.9992433,0.00004201768,0.00002770342,0.000368895],"study_design_scores_gemma":[0.00002581391,0.0004008156,0.02247768,0.00002412899,0.00003386669,0.0003117417,0.00009727584,0.00272002,0.9712828,0.0001717418,0.002429274,0.00002494379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968969,0.0005677235,0.001072389,0.00009368863,0.00003343312,0.00001819779,0.0002810092,0.0000915007,0.0009452264],"genre_scores_gemma":[0.9951513,0.0004504524,0.00200655,0.00009083041,0.000006838669,0.00005239493,0.0002597543,0.00003930286,0.001942486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001107032,"threshold_uncertainty_score":0.00319308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01881731754070584,"score_gpt":0.2279760173325934,"score_spread":0.2091586997918875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}